Hyperbranched polyesterpolyols as components of amperometric monoamine oxidase biosensors based on electrodes modified with nanomaterials for determination of antidepressants


如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅存取

详细

The use of hyperbranched polyesterpolyols of different generations favors firmer fixation of carbon nanotubes and silver nanoparticles as components of composite materials on the electrode surface (0.028 mg cm–2), which improves the operation characteristics of monoamine oxidase biosensors. The size of silver nanoparticles (18–52 nm) depends on the conditions for preparing hyperbranched polyesterpolyols, and their use as electrode modifiers influences the analytical possibilities of amperometric biosensors. Silver nanoparticles (18 nm, data of atomic force microscopy) in polyesterpolyols of third generation (pH 10.0) as components of the developed biosensors extend the interval of determinable concentrations to 1 × 10–4–1 × 10–8 M and decrease the lower limit of determination to 3 × 10–9 M, compared to the unmodified sensors, owing to enhancement of the analytical signal. The developed biosensors were tested in monitoring of drugs (antidepressants) in Coaxil and Auroriks drug forms with the relative standard deviation on the level of 0.052.

作者简介

E. Medyantseva

Butlerov Chemical Institute

编辑信件的主要联系方式.
Email: emedyant@gmail.com
俄罗斯联邦, ul. Kremlevskaya 1/29, Kazan, Tatarstan, 420111

D. Brusnitsyn

Butlerov Chemical Institute

Email: emedyant@gmail.com
俄罗斯联邦, ul. Kremlevskaya 1/29, Kazan, Tatarstan, 420111

R. Varlamova

Butlerov Chemical Institute

Email: emedyant@gmail.com
俄罗斯联邦, ul. Kremlevskaya 1/29, Kazan, Tatarstan, 420111

O. Medvedeva

Butlerov Chemical Institute

Email: emedyant@gmail.com
俄罗斯联邦, ul. Kremlevskaya 1/29, Kazan, Tatarstan, 420111

M. Kutyreva

Butlerov Chemical Institute

Email: emedyant@gmail.com
俄罗斯联邦, ul. Kremlevskaya 1/29, Kazan, Tatarstan, 420111

N. Ulakhovich

Butlerov Chemical Institute

Email: emedyant@gmail.com
俄罗斯联邦, ul. Kremlevskaya 1/29, Kazan, Tatarstan, 420111

A. Fattakhova

Institute of Fundamental Medicine and Biology

Email: emedyant@gmail.com
俄罗斯联邦, ul. Karla Marksa 74, Kazan, Tatarstan, 420055

O. Konovalova

Institute of Physics, Kazan (Volga) Federal University

Email: emedyant@gmail.com
俄罗斯联邦, ul. Kremlevskaya 18, Kazan, Tatarstan, 420111

G. Budnikov

Butlerov Chemical Institute

Email: emedyant@gmail.com
俄罗斯联邦, ul. Kremlevskaya 1/29, Kazan, Tatarstan, 420111

补充文件

附件文件
动作
1. JATS XML

版权所有 © Pleiades Publishing, Ltd., 2017