Crystal Structure and Anti-kidney Cancer Activity of Two Novel Coordination Polymers {[Cu2(DCTP)2](H2O)}n and {[Zn5(NTB)4(DMF)2](NH2NMe2)(DMF)3}n

Abstract

Two new coordination polymers, namely {[Cu₂(DCTP)₂](H₂O)}_n (I) (H₂DCTP = 4'-(3,5-dicarboxyphenyl)-4,2':6',4''-terpyridine) and {[Zn₅(NTB)₄(DMF)₂](H₂NMe₂)₂(DMF)₃}_n (II) (H₃NTB = 4,4′,4″-nitrilotribenzoic acid, DMF = N,N-dimethylformamide), have been successfully constructed under solvothermal conditions. The structures of two complexes have been successfully determined by single crystal X-ray diffraction (CIF files CCDC nos. 1852377 (I) and 1852378 (II)). In addition, in vitro antitumor activity of compounds I and II on four human kidney cancer cells (GRC-1, A-498, ACHN and 786-P) was further determined and the results show that the two compounds showed promising activity.