Influence of the external noise intensity on the kinetics of ligands binding to receptors

V. B. Arakelyan; V. P. Danko; R. P. Grigoryan

doi:10.3103/S106833721701011X

Influence of the external noise intensity on the kinetics of ligands binding to receptors

Authors: Arakelyan V.B.¹, Danko V.P.², Grigoryan R.P.¹
Affiliations:
1. Yerevan State University
2. Krasnodar Branch of the Plekhanov Russian University of Economics
Issue: Vol 52, No 1 (2017)
Pages: 70-75
Section: Article
URL: https://journals.rcsi.science/1068-3372/article/view/228273
DOI: https://doi.org/10.3103/S106833721701011X
ID: 228273

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Abstract
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Abstract

The average, variance, correlation function and the spectral density of ligand–receptor complexes in the presence of the external Langevin noise are calculated and their characteristics are defined. The analysis of the experimental data using the formulas derived in this work enables one to obtain a new information on the process of forming of ligand–receptor complex, namely, the constants rates of formation and the decay of the ligand–receptor complex.