Methods for obtaining solid dispersions of drugs and their properties
- 作者: Khalikov S.1, Lokshin B.1, Ilyin M.1, Varlamova A.2, Musaev M.2, Arhipov I.2
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隶属关系:
- A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
- All-Russian Research Institute of Fundamental and Applied Parasitology of Animals and Plants – Branch of the Federal State Budgetary Scientific Institution “Federal Scientific Center – K. I. Skryabin and Ya. R. Kovalenko All-Russian Scientific Research Institute of Experimental Veterenary Medicine”, Russian Academy of Sciences
- 期: 卷 68, 编号 10 (2019)
- 页面: 1924-1932
- 栏目: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/243509
- DOI: https://doi.org/10.1007/s11172-019-2648-3
- ID: 243509
如何引用文章
详细
The possibility of improving the solubility of drugs by obtaining solid dispersions (SDs) with polymers is demonstrated. The solubility of these SDs is dependent both on the nature of drug and polymer and on the conditions of their preparation. IR spectroscopy of the obtained SDs and the analysis of results found in literature indicate that inclusion complexes are formed within them.
作者简介
S. Khalikov
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: salavatkhalikov@mail.ru
俄罗斯联邦, 28 ul. Vavilova, Moscow, 119991
B. Lokshin
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
Email: salavatkhalikov@mail.ru
俄罗斯联邦, 28 ul. Vavilova, Moscow, 119991
M. Ilyin
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
Email: salavatkhalikov@mail.ru
俄罗斯联邦, 28 ul. Vavilova, Moscow, 119991
A. Varlamova
All-Russian Research Institute of Fundamental and Applied Parasitology of Animals and Plants – Branch of the Federal State Budgetary Scientific Institution “Federal Scientific Center – K. I. Skryabin and Ya. R. Kovalenko All-Russian Scientific Research Institute of Experimental Veterenary Medicine”, Russian Academy of Sciences
Email: salavatkhalikov@mail.ru
俄罗斯联邦, 28 ul. B. Cheremushkinskaya, Moscow, 117218
M. Musaev
All-Russian Research Institute of Fundamental and Applied Parasitology of Animals and Plants – Branch of the Federal State Budgetary Scientific Institution “Federal Scientific Center – K. I. Skryabin and Ya. R. Kovalenko All-Russian Scientific Research Institute of Experimental Veterenary Medicine”, Russian Academy of Sciences
Email: salavatkhalikov@mail.ru
俄罗斯联邦, 28 ul. B. Cheremushkinskaya, Moscow, 117218
I. Arhipov
All-Russian Research Institute of Fundamental and Applied Parasitology of Animals and Plants – Branch of the Federal State Budgetary Scientific Institution “Federal Scientific Center – K. I. Skryabin and Ya. R. Kovalenko All-Russian Scientific Research Institute of Experimental Veterenary Medicine”, Russian Academy of Sciences
Email: salavatkhalikov@mail.ru
俄罗斯联邦, 28 ul. B. Cheremushkinskaya, Moscow, 117218