Methods for obtaining solid dispersions of drugs and their properties


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The possibility of improving the solubility of drugs by obtaining solid dispersions (SDs) with polymers is demonstrated. The solubility of these SDs is dependent both on the nature of drug and polymer and on the conditions of their preparation. IR spectroscopy of the obtained SDs and the analysis of results found in literature indicate that inclusion complexes are formed within them.

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S. Khalikov

A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences

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Email: salavatkhalikov@mail.ru
俄罗斯联邦, 28 ul. Vavilova, Moscow, 119991

B. Lokshin

A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences

Email: salavatkhalikov@mail.ru
俄罗斯联邦, 28 ul. Vavilova, Moscow, 119991

M. Ilyin

A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences

Email: salavatkhalikov@mail.ru
俄罗斯联邦, 28 ul. Vavilova, Moscow, 119991

A. Varlamova

All-Russian Research Institute of Fundamental and Applied Parasitology of Animals and Plants – Branch of the Federal State Budgetary Scientific Institution “Federal Scientific Center – K. I. Skryabin and Ya. R. Kovalenko All-Russian Scientific Research Institute of Experimental Veterenary Medicine”, Russian Academy of Sciences

Email: salavatkhalikov@mail.ru
俄罗斯联邦, 28 ul. B. Cheremushkinskaya, Moscow, 117218

M. Musaev

All-Russian Research Institute of Fundamental and Applied Parasitology of Animals and Plants – Branch of the Federal State Budgetary Scientific Institution “Federal Scientific Center – K. I. Skryabin and Ya. R. Kovalenko All-Russian Scientific Research Institute of Experimental Veterenary Medicine”, Russian Academy of Sciences

Email: salavatkhalikov@mail.ru
俄罗斯联邦, 28 ul. B. Cheremushkinskaya, Moscow, 117218

I. Arhipov

All-Russian Research Institute of Fundamental and Applied Parasitology of Animals and Plants – Branch of the Federal State Budgetary Scientific Institution “Federal Scientific Center – K. I. Skryabin and Ya. R. Kovalenko All-Russian Scientific Research Institute of Experimental Veterenary Medicine”, Russian Academy of Sciences

Email: salavatkhalikov@mail.ru
俄罗斯联邦, 28 ul. B. Cheremushkinskaya, Moscow, 117218


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