Chemospecific synthesis of 2-acetoxyindole-3-carbonitriles catalyzed by Cu(acac)2


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A chemospecific one-pot synthesis of easily isolable 2-acetoxyindole-3-carbonitriles was described. The intermediate 2-oxindole-3-carbonitriles successfully prepared from 2-cyano diazoacetanilides without isolation were treated with acetyl chloride and triethylamine to give 2-acetoxyindole-3-carbonitriles. The developed one-pot approach showed broad substrate scope.

作者简介

Shanyan Mo

State Key Laboratory of Chemical Engineering Resource, Department of Organic Chemistry, Faculty of Science, Beijing University of Chemical Technology

Email: jxxu@mail.buct.edu.cn
中国, Beijing, 100029

Jianzhuo Tu

State Key Laboratory of Chemical Engineering Resource, Department of Organic Chemistry, Faculty of Science, Beijing University of Chemical Technology

Email: jxxu@mail.buct.edu.cn
中国, Beijing, 100029

Jiaxi Xu

State Key Laboratory of Chemical Engineering Resource, Department of Organic Chemistry, Faculty of Science, Beijing University of Chemical Technology

编辑信件的主要联系方式.
Email: jxxu@mail.buct.edu.cn
中国, Beijing, 100029

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