Отправить статью по E-mail Analysis of racemic conjugates of purine with heterocyclic amines by chiral high-performance liquid chromatography
- Авторы: Tumashov A.A.1,2, Gruzdev D.A.1, Vigorov A.Y.1, Musiyak V.V.1, Chulakov E.N.1, Levit G.L.1, Krasnov V.P.1, Charushin V.N.1,3
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Учреждения:
- I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
- Institute of Natural Sciences and Mathematics, Ural Federal University
- Institute of Chemical Engineering, Ural Federal University
- Выпуск: Том 67, № 9 (2018)
- Страницы: 1704-1709
- Раздел: Article
- URL: https://journals.rcsi.science/1066-5285/article/view/243018
- DOI: https://doi.org/10.1007/s11172-018-2279-0
- ID: 243018
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Аннотация
Reversed-phase HPLC on chiral stationary phases was used to study the influence of the structure of purine and 2-aminopurine conjugates with chiral heterocyclic amines on the retention times. The optimum conditions for separation of enantiomers were found. The best parameters of separation of stereoisomers of all the compounds examined were achieved on a (S,S)-Whelk-O1 column in weakly alkaline aqueous methanol systems.
Об авторах
A. Tumashov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Institute of Natural Sciences and Mathematics, Ural Federal University
Email: izvan@ioc.ac.ru
Россия, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990; 19 ul. Mira, Ekaterinburg, 620002
D. Gruzdev
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: izvan@ioc.ac.ru
Россия, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990
A. Vigorov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: izvan@ioc.ac.ru
Россия, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990
V. Musiyak
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: izvan@ioc.ac.ru
Россия, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990
E. Chulakov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: izvan@ioc.ac.ru
Россия, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990
G. Levit
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: izvan@ioc.ac.ru
Россия, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990
V. Krasnov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: izvan@ioc.ac.ru
Россия, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990
V. Charushin
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Institute of Chemical Engineering, Ural Federal University
Email: izvan@ioc.ac.ru
Россия, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990; 19 ul. Mira, Ekaterinburg, 620002
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