Enviar artigo por via de e-mail Synthesis of new acridine-9-carboxylic acid derivatives
- Autores: Melyshenkova V.V.1, Kuznetsov D.N.1, Ruchkina A.G.1, Kobrakov K.I.1
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Afiliações:
- А. N. Kosygin Russian State University “Technologies. Design. Art”, Chair of Organic Chemistry
- Edição: Volume 67, Nº 5 (2018)
- Páginas: 878-883
- Seção: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/242534
- DOI: https://doi.org/10.1007/s11172-018-2152-1
- ID: 242534
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Resumo
New 1,3-dihydroxyacridine-9-carboxylic acids were obtained by Pfitzinger reaction from 2,4,6-trihydroxytoluene (methylphloroglucinol). Their bromination and azo-coupling reactions were studied. Computer simulation was used to determine potential pharmacokinetic and toxic properties of the synthesized compounds.
Sobre autores
V. Melyshenkova
А. N. Kosygin Russian State University “Technologies. Design. Art”, Chair of Organic Chemistry
Email: occd@mail.ru
Rússia, 1 ul. Malaya Kaluzhskaya, Moscow, 119991
D. Kuznetsov
А. N. Kosygin Russian State University “Technologies. Design. Art”, Chair of Organic Chemistry
Autor responsável pela correspondência
Email: occd@mail.ru
Rússia, 1 ul. Malaya Kaluzhskaya, Moscow, 119991
A. Ruchkina
А. N. Kosygin Russian State University “Technologies. Design. Art”, Chair of Organic Chemistry
Email: occd@mail.ru
Rússia, 1 ul. Malaya Kaluzhskaya, Moscow, 119991
K. Kobrakov
А. N. Kosygin Russian State University “Technologies. Design. Art”, Chair of Organic Chemistry
Email: occd@mail.ru
Rússia, 1 ul. Malaya Kaluzhskaya, Moscow, 119991
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