Отправить статью по E-mail Hydroxy- and alkoxymethylation of polyfluoroalkyl pyrazoles
- Авторы: Ivanova А.1, Shchegol´kov E.1, Burgart Y.1, Saloutin V.1
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Учреждения:
- Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
- Выпуск: Том 67, № 3 (2018)
- Страницы: 521-524
- Раздел: Article
- URL: https://journals.rcsi.science/1066-5285/article/view/242351
- DOI: https://doi.org/10.1007/s11172-018-2104-9
- ID: 242351
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Аннотация
A synthetic route to 1-hydroxy- and 1-alkoxymethyl-3-polyfluoroalkylpyrazoles via regioselective N-hydroxy- and alkoxymethylation of N-unsubstituted pyrazoles with paraformaldehyde has been proposed. The alkoxyalkylation of polyfluoroalkylpyrazoles proceeds in aqueous-alcohol medium, whereas hydroxymethylation requires anhydrous conditions.
Об авторах
А. Ivanova
Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: saloutin@ios.uran.ru
Россия, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990
E. Shchegol´kov
Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: saloutin@ios.uran.ru
Россия, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990
Ya. Burgart
Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: saloutin@ios.uran.ru
Россия, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990
V. Saloutin
Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Автор, ответственный за переписку.
Email: saloutin@ios.uran.ru
Россия, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990
