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Nucleophilic C—H functionalization of arenes: a contribution to green chemistry


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Abstract

The review is focused on premises, features and scope of the reactions leading to the direct functionalization of the C—H bond in arenes by the action of nucleophiles. Practical importance and a contribution of synthetic approaches with minimal steps, the so called PASE- (pot-, atom-, and step-economic) processes, to green chemistry are also discussed.

About the authors

V. N. Charushin

I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the First President of Russia B. N. Yeltsin

Author for correspondence.
Email: charushin@ios.uran.ru
Russian Federation, 22 ul. S. Kovalevskoy/Akademicheskaya, Yekaterinburg, 620990; 19 ul. Mira, Yekaterinburg, 620002

O. N. Chupakhin

I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the First President of Russia B. N. Yeltsin

Email: charushin@ios.uran.ru
Russian Federation, 22 ul. S. Kovalevskoy/Akademicheskaya, Yekaterinburg, 620990; 19 ul. Mira, Yekaterinburg, 620002

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