2-Halobenzenesulfonyl chlorides in the synthesis of pyrido[2,1- c ][1,2,4]benzothiadiazine 5,5-dioxide derivatives

R. M. Shlenev; S. I. Filimonov; A. V. Tarasov; A. S. Danilova; P. A. Agat’ev; S. A. Ivanovskii

doi:10.1007/s11172-016-1518-5

2-Halobenzenesulfonyl chlorides in the synthesis of pyrido[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide derivatives

Authors: Shlenev R.M.¹, Filimonov S.I.¹, Tarasov A.V.¹, Danilova A.S.¹, Agat’ev P.A.¹, Ivanovskii S.A.²
Affiliations:
1. Yaroslavl State Technical University
2. K. D. Ushinsky Yaroslavl State Pedagogical University
Issue: Vol 65, No 7 (2016)
Pages: 1839-1845
Section: Full Articles
URL: https://journals.rcsi.science/1066-5285/article/view/238620
DOI: https://doi.org/10.1007/s11172-016-1518-5
ID: 238620

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Abstract

A number of new functional derivatives of pyrido[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide was obtained based on the reactions of 2-halobenzenesulfonyl chlorides with 2-aminopyridine derivatives. A quantitative criterion for the evaluation of a possibility for the reaction to proceed under noncatalytic conditions depending on the type of halogen and substituents in the starting compounds was suggested.