Potential of PET in Tumor Theranostics

Abstract

Targeted radionuclide therapy (TRT) is today one of the most effective methods for tumor treatment. The use of the theranostic concept allows personalized approach to the choice of treatment tactics, based on diagnostic investigation using molecular imaging methods, among which PET is the most sensitive and informative. The main theranostic isotope pairs and the corresponding radiopharmaceuticals for TRT, based on β-emitters used in clinical practice, are briefly considered, and the possibilities and limitations of the well-known agents and prospects for using new radiopharmaceuticals in TRT are discussed.