Preparation and Biodistribution of 99mTc-Trazodone as a Brain Imaging Probe

Аннотация

Trazodone was labeled with ^99mTc by indirect method. More than 97% radiochemical yield was reached under the following optimized conditions: 100 µg of Trazodone, pH 7, 10 mg of glucoheptonate, 35 µg of stannous chloride, 185 MBq of ^99mTc eluate, 20 min, room temperature. The in vitro stability and also the retention of the complex in the brain tissue allow the use of this complex as a potential brain imaging agent.