Identification of H-Bonds in a Calcified Aortic Valve
- Authors: Ivanov-Omskii V.I.1, Rutkovskii K.S.2, Gulyaev N.I.3, Galenko A.S.3, Yastrebov S.G.1
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Affiliations:
- Ioffe Physical Technical Institute, Russian Academy of Sciences
- St. Petersburg State University
- S.M. Kirov Military Medical Academy
- Issue: Vol 45, No 9 (2019)
- Pages: 927-929
- Section: Article
- URL: https://journals.rcsi.science/1063-7850/article/view/208430
- DOI: https://doi.org/10.1134/S1063785019090244
- ID: 208430
Cite item
Abstract
The IR absorption spectra of subendothelial regions of the aortic valve cusps of a patient with calcified aortic stenosis diagnosis were measured by the attenuated total reflectance (ATR) spectroscopy technique in a frequency interval of 2500–3600 cm–1 and analyzed in comparison to the spectra of healthy human tissues and reference spectra of a pig’s healthy bone and aortic valve. The IR absorption band structure in this spectral region was studied by means of expansion into Gaussian components. The energies of hydrogen bonds (H-bonds) involving O–H groups were estimated. It is established that, among all samples studied, the energy of H-bonds between hydroxyl groups reaches maximum in the bone tissue.
Keywords
About the authors
V. I. Ivanov-Omskii
Ioffe Physical Technical Institute, Russian Academy of Sciences
Email: yastrebov@mail.ioffe.ru
Russian Federation, St. Petersburg, 194021
K. S. Rutkovskii
St. Petersburg State University
Email: yastrebov@mail.ioffe.ru
Russian Federation, St. Petersburg, 199034
N. I. Gulyaev
S.M. Kirov Military Medical Academy
Email: yastrebov@mail.ioffe.ru
Russian Federation, St. Petersburg, 194044
A. S. Galenko
S.M. Kirov Military Medical Academy
Email: yastrebov@mail.ioffe.ru
Russian Federation, St. Petersburg, 194044
S. G. Yastrebov
Ioffe Physical Technical Institute, Russian Academy of Sciences
Author for correspondence.
Email: yastrebov@mail.ioffe.ru
Russian Federation, St. Petersburg, 194021