Double-Membrane Sampling System in a Mass Spectrometer for the Study of Exhaled Air
- Авторлар: Kogan V.1, Antonov A.1, Chichagov Y.1, Victorova-Leclerc O.1, Victorov I.1, Kozlenok A.2
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Мекемелер:
- Ioffe Institute
- Almazov Federal Medical Research Center
- Шығарылым: Том 63, № 10 (2018)
- Беттер: 1543-1551
- Бөлім: Experimental Instruments and Technique
- URL: https://journals.rcsi.science/1063-7842/article/view/202221
- DOI: https://doi.org/10.1134/S1063784218100146
- ID: 202221
Дәйексөз келтіру
Аннотация
A double-membrane sample-introduction system is described that enables mass spectrometric determination of volatile organic compounds in air, while ensuring their detection limits are as low as a few fractions of ppb of sample composition in real time with a response delay from a few seconds to a few dozens of seconds. It includes two membrane interfaces separated by a volume, the gas pressure in which is maintained through a channel with an adjustable evacuation cross-section. The results of numerical simulation and experimental testing of the system are provided. A technique for selecting and calculating system parameters is described. The possibility of using this system for diagnosing diseases by trace amounts of biomarkers in exhaled air is discussed.
Авторлар туралы
V. Kogan
Ioffe Institute
Хат алмасуға жауапты Автор.
Email: Viktor.Kogan@mail.ioffe.ru
Ресей, St. Petersburg, 194021
A. Antonov
Ioffe Institute
Email: Viktor.Kogan@mail.ioffe.ru
Ресей, St. Petersburg, 194021
Yu. Chichagov
Ioffe Institute
Email: Viktor.Kogan@mail.ioffe.ru
Ресей, St. Petersburg, 194021
O. Victorova-Leclerc
Ioffe Institute
Email: Viktor.Kogan@mail.ioffe.ru
Ресей, St. Petersburg, 194021
I. Victorov
Ioffe Institute
Email: Viktor.Kogan@mail.ioffe.ru
Ресей, St. Petersburg, 194021
A. Kozlenok
Almazov Federal Medical Research Center
Email: Viktor.Kogan@mail.ioffe.ru
Ресей, St. Petersburg, 197341