Biologically Active Hybrid Nanosystems Based on Zero-Valent Selenium Nanoparticles, Biocompatible Polymers, and Polyelectrolitic Complex
- Authors: Valueva S.V.1, Vylegzhanina M.E.1, Alekseeva P.E.1,2, Sukhanova T.E.1,3
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Affiliations:
- Institute of Macromolecular Compounds, Russian Academy of Sciences
- Peter the Great St. Petersburg Polytechnic University
- Lebedev Institute of Synthetic Rubber
- Issue: Vol 63, No 9 (2018)
- Pages: 1248-1253
- Section: Physical Approaches and Problems of Data Interpretation in the Life Sciences
- URL: https://journals.rcsi.science/1063-7842/article/view/201890
- DOI: https://doi.org/10.1134/S1063784218090232
- ID: 201890
Cite item
Abstract
The molecular-conformal, morphological, and kinetic characteristics of selenium-containing nanosystems (NSs) based of biocompatible polymer matrices of different origins modified Se0 nanoparticles for the Se0 : polymer mass ratio ν = 0.1 have been analyzed using static and dynamic light scattering methods, UV spectroscopy, flow birefringence, and atomic force and transmission electron microscopies. We have determined the rate constants for the formation of selenium-containing NSs, the size characteristics of the corresponding nanostructures, as well as their shape, molecular mass, and density. It is found that isolated dense spherical polymolecular selenium-containing nanostructures are formed in the aqueous solution. Our results can be used as the physicochemical foundation for the modification of polymer materials with clearly manifested physiological activity by biogenic elements in the zero-valent form.
About the authors
S. V. Valueva
Institute of Macromolecular Compounds, Russian Academy of Sciences
Author for correspondence.
Email: svalu67@mail.ru
Russian Federation, St. Petersburg, 199004
M. E. Vylegzhanina
Institute of Macromolecular Compounds, Russian Academy of Sciences
Email: svalu67@mail.ru
Russian Federation, St. Petersburg, 199004
P. E. Alekseeva
Institute of Macromolecular Compounds, Russian Academy of Sciences; Peter the Great St. Petersburg Polytechnic University
Email: svalu67@mail.ru
Russian Federation, St. Petersburg, 199004; St. Petersburg, 195251
T. E. Sukhanova
Institute of Macromolecular Compounds, Russian Academy of Sciences; Lebedev Institute of Synthetic Rubber
Email: svalu67@mail.ru
Russian Federation, St. Petersburg, 199004; St. Petersburg, 198035