Absolute Configuration of Andrographolide and Its Proliferation of Osteoblast Cell Lines
- Авторы: Chantrapromma S.1, Boonnak N.2, Pitakpornpreecha T.3, Yordthong T.3, Chidan Kumar C.S.4,5, Fun H.K.5
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Учреждения:
- Department of Chemistry, Faculty of Science
- Department of Basic Science and Mathematics, Faculty of Science
- Department of Biochemistry, Faculty of Science
- Department of Engineering Chemistry, Vidya Vikas Institute of Engineering and Technology
- X-ray Crystallography Unit, School of Physics
- Выпуск: Том 63, № 3 (2018)
- Страницы: 412-417
- Раздел: Structure of Organic Compounds
- URL: https://journals.rcsi.science/1063-7745/article/view/192518
- DOI: https://doi.org/10.1134/S1063774518030069
- ID: 192518
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Аннотация
Andrographolide, C20H30O5, is a labdane diterpenoid which was isolated from the leave of Andrographis paniculata. Its crystal structure is determined by single crystal X-ray diffraction: monoclinic, sp. gr. P21, Z = 2. Absolute configuration is determined by the refinement of the Flack parameter to 0.21(19). In the crystal, molecules are linked by O–H···O hydrogen bonds and C–H···O interactions into two dimensional network parallel to the (001) plane. Its proliferation of osteoblast cell lines is reported.
Об авторах
S. Chantrapromma
Department of Chemistry, Faculty of Science
Автор, ответственный за переписку.
Email: suchada_3p@hotmail.com
Таиланд, Hat-Yai, Songkhla, 90112
N. Boonnak
Department of Basic Science and Mathematics, Faculty of Science
Email: suchada_3p@hotmail.com
Таиланд, Songkhla, 90000
T. Pitakpornpreecha
Department of Biochemistry, Faculty of Science
Email: suchada_3p@hotmail.com
Таиланд, Hat-Yai, Songkhla, 90112
T. Yordthong
Department of Biochemistry, Faculty of Science
Email: suchada_3p@hotmail.com
Таиланд, Hat-Yai, Songkhla, 90112
C. Chidan Kumar
Department of Engineering Chemistry, Vidya Vikas Institute of Engineering and Technology; X-ray Crystallography Unit, School of Physics
Email: suchada_3p@hotmail.com
Индия, Karnataka, Mysuru, 570028; USM, Penang, 11800
H. Fun
X-ray Crystallography Unit, School of Physics
Email: suchada_3p@hotmail.com
Малайзия, USM, Penang, 11800
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