Мақаланы E-mail арқылы жіберу Comparison of the Structural Features of Micron and Submicron Vaterite Particles and Their Efficiency for Intranasal Delivery of Anesthetic to the Brain
- Авторлар: Trushina D.B.1,2,3, Borodina T.N.3,2, Sulyanov S.N.3,1, Moiseeva J.V.4, Gulyaeva N.V.4, Bukreeva T.V.1,3
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Мекемелер:
- National Research Centre “Kurchatov Institute,”
- Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation
- Shubnikov Institute of Crystallography, Federal Scientific Research Centre “Crystallography and Photonics,” Russian Academy of Sciences
- Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences
- Шығарылым: Том 63, № 6 (2018)
- Беттер: 998-1004
- Бөлім: Nanomaterials and Ceramics
- URL: https://journals.rcsi.science/1063-7745/article/view/193243
- DOI: https://doi.org/10.1134/S1063774518060305
- ID: 193243
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
Nanostructured spherical calcium carbonate particles with average sizes of 3.8 µm and 550 nm have been fabricated. Optimal conditions for adsorption of central anesthetic loperamide on these particles are found. The influence of particle size on the adsorption efficiency is studied. The efficiency of micron and submicron vaterite particles as carriers for intranasal loperamide delivery is compared using in vivo tests on laboratory animals.
Негізгі сөздер
Авторлар туралы
D. Trushina
National Research Centre “Kurchatov Institute,”; Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation; Shubnikov Institute of Crystallography, Federal Scientific Research Centre “Crystallography and Photonics,”Russian Academy of Sciences
Хат алмасуға жауапты Автор.
Email: trushina.d@mail.ru
Ресей, Moscow, 123182; Moscow, 119146; Moscow, 119333
T. Borodina
Shubnikov Institute of Crystallography, Federal Scientific Research Centre “Crystallography and Photonics,”Russian Academy of Sciences; Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation
Email: trushina.d@mail.ru
Ресей, Moscow, 119333; Moscow, 119146
S. Sulyanov
Shubnikov Institute of Crystallography, Federal Scientific Research Centre “Crystallography and Photonics,”Russian Academy of Sciences; National Research Centre “Kurchatov Institute,”
Email: trushina.d@mail.ru
Ресей, Moscow, 119333; Moscow, 123182
J. Moiseeva
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences
Email: trushina.d@mail.ru
Ресей, Moscow, 117485
N. Gulyaeva
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences
Email: trushina.d@mail.ru
Ресей, Moscow, 117485
T. Bukreeva
National Research Centre “Kurchatov Institute,”; Shubnikov Institute of Crystallography, Federal Scientific Research Centre “Crystallography and Photonics,”Russian Academy of Sciences
Email: trushina.d@mail.ru
Ресей, Moscow, 123182; Moscow, 119333
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