Protein crystallization under microgravity conditions. Analysis of the results of Russian experiments performed on the International Space Station in 2005−2015
- Authors: Boyko K.M.1,2, Timofeev V.I.1,3, Samygina V.R.1,3, Kuranova I.P.1,3, Popov V.O.1,2, Koval’chuk M.V.1,3
-
Affiliations:
- National Research Centre “Kurchatov Institute”
- Federal Research Centre “Fundamentals of Biotechnology”
- Shubnikov Institute of Crystallography of Federal Scientific Research Centre “Crystallography and Photonics,”
- Issue: Vol 61, No 5 (2016)
- Pages: 718-729
- Section: Reviews
- URL: https://journals.rcsi.science/1063-7745/article/view/190247
- DOI: https://doi.org/10.1134/S1063774516050059
- ID: 190247
Cite item
Abstract
Conditions of mass transport to growing crystals have a considerable effect on the crystal size and quality. The reduction of convective transport can help improve the quality of crystals for X-ray crystallography. One approach to minimizing convective transport is crystallization in a microgravity environment, in particular, in space. The data obtained by our research team in protein crystallization experiments on the International Space Station are surveyed and analyzed.
About the authors
K. M. Boyko
National Research Centre “Kurchatov Institute”; Federal Research Centre “Fundamentals of Biotechnology”
Author for correspondence.
Email: kmb@inbi.ras.ru
Russian Federation, pl. Akademika Kurchatova 1, Moscow, 123098; Leninskii pr. 33, Moscow, 119071
V. I. Timofeev
National Research Centre “Kurchatov Institute”; Shubnikov Institute of Crystallography of Federal Scientific Research Centre “Crystallography and Photonics,”
Email: kmb@inbi.ras.ru
Russian Federation, pl. Akademika Kurchatova 1, Moscow, 123098; Leninskii pr. 59, Moscow, 119333
V. R. Samygina
National Research Centre “Kurchatov Institute”; Shubnikov Institute of Crystallography of Federal Scientific Research Centre “Crystallography and Photonics,”
Email: kmb@inbi.ras.ru
Russian Federation, pl. Akademika Kurchatova 1, Moscow, 123098; Leninskii pr. 59, Moscow, 119333
I. P. Kuranova
National Research Centre “Kurchatov Institute”; Shubnikov Institute of Crystallography of Federal Scientific Research Centre “Crystallography and Photonics,”
Email: kmb@inbi.ras.ru
Russian Federation, pl. Akademika Kurchatova 1, Moscow, 123098; Leninskii pr. 59, Moscow, 119333
V. O. Popov
National Research Centre “Kurchatov Institute”; Federal Research Centre “Fundamentals of Biotechnology”
Email: kmb@inbi.ras.ru
Russian Federation, pl. Akademika Kurchatova 1, Moscow, 123098; Leninskii pr. 33, Moscow, 119071
M. V. Koval’chuk
National Research Centre “Kurchatov Institute”; Shubnikov Institute of Crystallography of Federal Scientific Research Centre “Crystallography and Photonics,”
Email: kmb@inbi.ras.ru
Russian Federation, pl. Akademika Kurchatova 1, Moscow, 123098; Leninskii pr. 59, Moscow, 119333
Supplementary files
