Protein crystallization under microgravity conditions. Analysis of the results of Russian experiments performed on the International Space Station in 2005−2015


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Abstract

Conditions of mass transport to growing crystals have a considerable effect on the crystal size and quality. The reduction of convective transport can help improve the quality of crystals for X-ray crystallography. One approach to minimizing convective transport is crystallization in a microgravity environment, in particular, in space. The data obtained by our research team in protein crystallization experiments on the International Space Station are surveyed and analyzed.

About the authors

K. M. Boyko

National Research Centre “Kurchatov Institute”; Federal Research Centre “Fundamentals of Biotechnology”

Author for correspondence.
Email: kmb@inbi.ras.ru
Russian Federation, pl. Akademika Kurchatova 1, Moscow, 123098; Leninskii pr. 33, Moscow, 119071

V. I. Timofeev

National Research Centre “Kurchatov Institute”; Shubnikov Institute of Crystallography of Federal Scientific Research Centre “Crystallography and Photonics,”

Email: kmb@inbi.ras.ru
Russian Federation, pl. Akademika Kurchatova 1, Moscow, 123098; Leninskii pr. 59, Moscow, 119333

V. R. Samygina

National Research Centre “Kurchatov Institute”; Shubnikov Institute of Crystallography of Federal Scientific Research Centre “Crystallography and Photonics,”

Email: kmb@inbi.ras.ru
Russian Federation, pl. Akademika Kurchatova 1, Moscow, 123098; Leninskii pr. 59, Moscow, 119333

I. P. Kuranova

National Research Centre “Kurchatov Institute”; Shubnikov Institute of Crystallography of Federal Scientific Research Centre “Crystallography and Photonics,”

Email: kmb@inbi.ras.ru
Russian Federation, pl. Akademika Kurchatova 1, Moscow, 123098; Leninskii pr. 59, Moscow, 119333

V. O. Popov

National Research Centre “Kurchatov Institute”; Federal Research Centre “Fundamentals of Biotechnology”

Email: kmb@inbi.ras.ru
Russian Federation, pl. Akademika Kurchatova 1, Moscow, 123098; Leninskii pr. 33, Moscow, 119071

M. V. Koval’chuk

National Research Centre “Kurchatov Institute”; Shubnikov Institute of Crystallography of Federal Scientific Research Centre “Crystallography and Photonics,”

Email: kmb@inbi.ras.ru
Russian Federation, pl. Akademika Kurchatova 1, Moscow, 123098; Leninskii pr. 59, Moscow, 119333

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