Detonation nanodiamonds as antioxidants in various test systems
- Autores: Shugalei I.V.1, Borovikova A.S.1, Voznyakovskii A.P.2, Ilyushin M.A.1
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Afiliações:
- St. Petersburg State Institute of Technology (Technical University)
- Acad. S. V. Lebedev Research Institute for Synthetic Rubber
- Edição: Volume 39, Nº 5 (2017)
- Páginas: 326-335
- Seção: Production, Structure, Properties
- URL: https://journals.rcsi.science/1063-4576/article/view/185961
- DOI: https://doi.org/10.3103/S1063457617050045
- ID: 185961
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Resumo
Detonation nanodiamonds (DND) are shown to exhibit antioxidant activity both in vitro and in vivo. DNDs, when introduced into laboratory animals by oral delivery, decrease protein peroxidation in erythrocytes, inhibit peroxidation of lipids and proteins in blood plasma. In case a pro-oxidant, NaNO2, is administered to animals, DND also protects them against the chemically induced oxidative stress. The results of the testing provide the experimental basis for recommending DND as a potential antioxidant for correcting oxidative damage of different origin.
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Sobre autores
I. Shugalei
St. Petersburg State Institute of Technology (Technical University)
Email: apvozn@gmail.com
Rússia, Moskovskii pr. 26, St. Petersburg, 190005
A. Borovikova
St. Petersburg State Institute of Technology (Technical University)
Email: apvozn@gmail.com
Rússia, Moskovskii pr. 26, St. Petersburg, 190005
A. Voznyakovskii
Acad. S. V. Lebedev Research Institute for Synthetic Rubber
Autor responsável pela correspondência
Email: apvozn@gmail.com
Rússia, ul. Gapsal’skaya 1, St. Petersburg, 198035
M. Ilyushin
St. Petersburg State Institute of Technology (Technical University)
Email: apvozn@gmail.com
Rússia, Moskovskii pr. 26, St. Petersburg, 190005
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