Localizing the Nanodeformation Impact of Magnetic Nanoparticles on Macromolecular Objects by Physical and Biochemical Means


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Аннотация

A new magnetomechanical approach in biomedicine is described. It is based on the rotational oscillations of magnetic nanoparticles (MNPs) in a non-heating magnetic field (MF) at frequencies of 0.1–1000 Hz. Nanodeformations induced in associated macromolecules can be used for selective control of their properties. Models of local molecular effects are presented, and the possibility of inducing biochemical responses through the deformation of biomembranes and membrane structures is assessed. A way of macroscopically limiting the MNP activation volume in a gradient MF is proposed.

Авторлар туралы

Yu. Golovin

Research Institute Nanotechnologies and Nanomaterials; Moscow State University; National University of Science and Technology MISiS; University of North Carolina

Хат алмасуға жауапты Автор.
Email: nano@tsutmb.ru
Ресей, Tambov, 392000; Moscow, 119991; Moscow, 119049; Chapel Hill, 27599

Al. Zhigachev

Research Institute Nanotechnologies and Nanomaterials

Email: nano@tsutmb.ru
Ресей, Tambov, 392000

N. Klyachko

Moscow State University; National University of Science and Technology MISiS

Email: nano@tsutmb.ru
Ресей, Moscow, 119991; Moscow, 119049

A. Kabanov

Moscow State University; University of North Carolina

Email: nano@tsutmb.ru
Ресей, Moscow, 119991; Chapel Hill, 27599

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© Allerton Press, Inc., 2018