Spectral Analysis of Spongy Bone Tissue after Ovariectomy and the Efficacy of Recovery Using Allogeneic Hydroxyapatite

Abstract

During the work, experimental studies of spongy bone tissue of animals after ovariectomy and evaluation of its regeneration by allogeneic hydroxyapatite (HAP) by Raman spectroscopy were carried out. Also deconvolution of Raman spectra of the studied samples was carried out. Coefficients allow to evaluate the efficiency of HAP for the correction of osteoresorption in modeling osteoporosis with ovariectomy were entered. HAP suspension treatment leads to partial compensation of ovariectomy effect in the spongy bone tissue.