Email this article THE EFFECT OF HERBAL MEDICINE ON THE IMMEDIATE INDICATORS OF HOMEOSTASIS IN PATIENTS WITH LOCALLY ADVANCED CERVICAL CANCER WHO RECEIVED SPECIAL TREATMENT
- Authors: Korepanov S.V1, Lazarev A.F1,2, Petrova V.D.2
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Affiliations:
- Altai State Medical University of the Ministry of health of the Russian Federation
- Altai Branch N.N. Blokhin National Medical Research Centre of Oncology of Health Ministry of Russia
- Issue: Vol 23, No 3-6 (2018)
- Pages: 158-163
- Section: Articles
- URL: https://journals.rcsi.science/1028-9984/article/view/42979
- DOI: https://doi.org/10.18821/1028-9984-2018-23-3-6-158-163
- ID: 42979
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Abstract
Radiation therapy is the main method of treatment of locally advanced cervical cancer. However, this type of treatment, especially in combination with chemotherapy, often leads to complications from the indicators of homeostasis. The authors proposed to eliminate or mitigate hematological side effects to use as an accompanying therapy during chemo-radiation treatment of the original patented method of drugs from medicinal plants. There are Siberian ginseng (Eleutherococcus senticosus Maxim.), Badan (bergenia crassifolia), Birch buds (Gemmae Betulae), Pharmacy Chamomile (Matricaria Chamomilla), Plantago (Plantago major L.), St. John’s wort (Hypericum perforatum L. ), Licorice root (Glycirrhiza glabra uralensis L.), Bearberry (Arctostaphylos uva-ursi Spr.), Yarrow (Achillea millefolium L.), Dill (Anethum graveolens L.), Linseed (Linum usitatissimum L.) in the original method. In a randomized clinical trial in patients with locally advanced cervical cancer: primary group of 350 patients who received standard special chemo-radiation therapy on the background of the accompanying herbal medicine and a comparison group - 402 patients who received only standard, the special treatment have been examined a number of indicators of homeostasis. It was shown that in patients of the main group, the deviation from the normal level of blood parameters were less pronounced and returned to normal faster after treatment than in patients of the comparison group (p<0.01).
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##article.viewOnOriginalSite##About the authors
S. V Korepanov
Altai State Medical University of the Ministry of health of the Russian Federation656049, Barnaul, Russian Federation
A. F Lazarev
Altai State Medical University of the Ministry of health of the Russian Federation; Altai Branch N.N. Blokhin National Medical Research Centre of Oncology of Health Ministry of Russia656049, Barnaul, Russian Federation; 656049, Barnaul, Russian Federation
Valentina D. Petrova
Altai Branch N.N. Blokhin National Medical Research Centre of Oncology of Health Ministry of Russia
Email: valent_04@mail.ru
MD, PhD, leading researcher of the laboratory for the study of epidemiology and cancer prevention of the Altai Branch of “NMIC Oncology. N. N. Blokhin” of The Russian Ministry of Health, 656049, Barnaul, Russian Federation 656049, Barnaul, Russian Federation
References
- Бойко А.В. и др. Рак шейки матки. В кн.: Каприн А.Д., Мардынский Ю.С. , ред. Терапевтическая радиология. Национальное руководство. М.: ГЭОТАР-Медиа, 2018; 479-91.
- Бохман Я.В. Руководство по онкогинекологии. М.: Книга по Требованию. 2012. 464 с.
- Клинические рекомендации по диагностике и лечению рака шейки матки. Ассоциация онкологов России. М., 2017. 38 c.
- Чиссов В.И., Давыдов М.И., ред. Онкология. Национальное руководство. Краткое издание М.: ГЭОТАР-Медиа, 2017. 576 с.
- Переводчикова Н.И., Горбунова В.А., ред. Руководство по химиотерапии опухолевых заболеваний. 4-е изд. расширенное и дополненное. М.: Практическая медицина. 2018; 19-22; 241-294; 581-607; 655.
- Хохлова С.В. и др. Практические рекомендации по лекарственному лечению рака шейки матки. Злокачественные опухоли. Практические рекомендации RUSSCO. ISSN 2587-6813 (электронное издание) 2018; 8 (3). Спецвыпуск 2. - 178-89.
- Лесиовская Е.Е. Доказательная фитотерапия. М.: Ремедиум, 2014. Т. II. - 688 c.
- Wichtl M., ed. Herbal Drugs and Phytopharmaceuticals. A Handbook for Practice on a Scientific Basis. Medpharm, Scientific Publishers Stuttgart. 2004.
- Bleakney T.L. Deconstructing an adaptogen: Eleutherococcus senticosus. Holist Nurs. Pract. 2008; 22 (4): 220-4.
- Fons F., Gargadennec A., Rapior S. Culture of Plantago species as bioactive component resourses: a 20-year review and recent applications. Acta Bot. Gallica. 2008; 155 (2): 277-300.
- Ronsted N. Chemotaxonomy and evolution of Plantago L. Plant Systematics and Evolution. 2003; 242 (1-4): 63-82.
- Vacek J., Klejdus B., Kubán V. Hypericin and hyperforin: bioactive components of St. John’s Wort (Hypericum perforatum). Their isolation, analysis and study of physiological effect. Ceska Slov. Farm. 2007; 56 (2): 62-6.
- Kokoska L. Screening of some Siberian medicinal plants for antimicrobial activity. J. Ethnopharmacol. 2002; 82 (1): 51-53.
- Гольдберг Е.Д., Зуева З.П. Препараты из лекарственных растений в комплексной терапии злокачественных новообразований. Томск, 2000. С. 130.
- Гольдберг Е.Д. и др. Влияние экстрактов из лекарственных растений на развитие метастатического процесса. Бюлл. экспер. биол. и мед. 2004; 138 (9): 324-32.
- Гольдберг Е.Д. и др. Растения в комплексной терапии опухолей. М.: Издательство РАМН. 2008. 232 с.
- Корсун В.Ф., Трескунов, Е. В. Корсун, А. Мицконас. Лекарственные растения в онкологии. 2-е изд. испр. и доп. СПб: Эко-Вектор. 2017. 432 с.
- Толмачевой Е.А., ред. Справочник ВИДАЛЬ 2019 Лекарственные препараты в России. Видал Рус. 2019. 1200 с.
- Корепанов С.В., Лазарев А.Ф., Веряскина Н.Д. Способ профилактики и лечения осложнений при лучевой и/или химиотерапии рака различной локализации. Патент РФ № 2322999, 27.04.2008 г.
