CLINICAL EXPERIENCE OF THE USE OF PD-1 INHIBITOR IN PATIENTS WITH NON-CELL LUNG CANCER WITH METASTATIC DAMAGE OF KIDNEYS AND ADRENALS


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Abstract

Non-small cell lung cancer (NSCLC) is the leading cause of death from cancer worldwide. Despite the success over recent years in the treatment of NSCLC it has not yet been able to achieve good long-term survival. A new promising direction of NSCLC treatment in the second line is the use of immunotherapy by inhibitors of immune control points. This group of drugs radically changed the outlook on the prognosis of patients with disseminated NSCLC progressing on previous platinum-containing chemotherapy. The article presents the results of a clinical trial program for nivolumab and the analysis of clinical cases of its application in NSCLC patients with metastatic damage of the kidneys and adrenal glands.

About the authors

Ksenya A. Sarantseva

N.N. Blokhin National Medical Research Center of Oncology

Email: sarantsevaka@gmail.com
MD, Postgraduate of the Department of Clinical Biotechnololgies, Moscow, 115478, Russian Federation. Moscow, 115478, Russian Federation

D. I Yudin

N.N. Blokhin National Medical Research Center of Oncology

Moscow, 115478, Russian Federation

M. A Okruzhnova

N.N. Blokhin National Medical Research Center of Oncology

Moscow, 115478, Russian Federation

K. P Laktionov

N.N. Blokhin National Medical Research Center of Oncology

Moscow, 115478, Russian Federation

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