CELL, RADIATION, AND CARCINOGENESIS

It has been suggested that there is an exceptional (unique) mechanism for incorporation into the genome of a reserve somatic cell during repair of radiation-induced DNA damages and that the latter cannot be included during replication. There are various cellular reproductive potentials (CRP) in different body anatomic systems, which differ in high radiosensitivity and resistance to carcinogenesis. As CRP is depleted and reproductive renewal is impossible, the reparative mechanism is used, which causes an increase in carcinogenesis rates. Whether carcinogenic signs can be involved with their verified presence in the human body and whether the cell genome contains new carcinogenic signs, such fibrolysis and osteolysis, are considered.

cell, radiation, carcinogenesis