Email this article ROLE OF EPITHELIAL ANTIGEN BER-EP4 IN THE STUDY OF EXUDATES FROM SEROUS SACS
- Authors: Volchenko N.N.1, Borisova O.V.1
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Affiliations:
- P. A. Herzen Moscow Oncology Research Institute, Ministry of Health and Social Development of the Russian Federation
- Issue: Vol 17, No 2 (2012)
- Pages: 18-22
- Section: Articles
- URL: https://journals.rcsi.science/1028-9984/article/view/39928
- DOI: https://doi.org/10.17816/onco39928
- ID: 39928
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Abstract
Herzen Moscow Oncology Research Institute, Ministry of Health and Social Development of the Russian Federation Serous exudates with epithelial antigen BER-EP4 were studied using immunoperoxidase, immunofluorescence, and immunocytochemical methods and by a laser flow cytoflurometric technique. Up-to-date high-technologies make it possible to detect few tumor complexes in the exudate at early metastatic stages, which are undetectable by the routine cytological assay and to decrease the rate of hyperdiagnosis of a tumor process. The high efficiency and rapidity of immunofluorescence study of exudates are shown to establish the extent of the tumor process during urgent intraoperative studies.
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##article.viewOnOriginalSite##About the authors
N. N. Volchenko
P. A. Herzen Moscow Oncology Research Institute, Ministry of Health and Social Development of the Russian Federation
Email: mnioi@mail.ru
д-р мед. наук, проф., рук. отд-ния онкоцитологии
O. V. Borisova
P. A. Herzen Moscow Oncology Research Institute, Ministry of Health and Social Development of the Russian Federation
References
- Выпотные жидкости / Долгов В. В., Шабалова И. П., Миронова И. И. и др. — Тверь: Триада, 2006.
- Глузман Д. Ф., Скляренко Л. М., Надгорная В. А., Крячок И. А. Диагностическая иммуноцитохимия опухолей. — Киев, 2003.
- Климанова З. Ф. Цитоморфологическая характеристика экссудатов при новообразованиях брюшины и плевры: Дис.. канд. мед. наук. — М., 1965.
- Петров С. В., Райхлин Н. Т. Руководство по иммуногистохимической диагностике опухолей человека. — Казань, 2004.
- Angelis M. D., Buley I. D., Heryet A., Gray W. / Cytopathology. — 2007. — Vol. 3, N 2. — P. 111—127.
- Bjorn R., Ben D., Hiep D. // J. Clin. Pathol. — 2000. — Vol. 53, N 7. — P. 513—517.
- Cardozo L. L. Atlas of clinical cytology. — Amsterdam, 1975.
- Dabbs D. J. Diagnostic immunohistochemistry. — Edinburgh, 2006.
- Risberg B., Davidson B., Dong H. et al. // J. Clin. Pathol. — 2000. — Vol. 53, N 7. — P. 513—517.
- Shidham V. B., Atkinson B. F. Cytophathologic diagnosis of serous fluids. — Philadelphia: Saunders Elsevier, 2007.
