CLINICO-IMMUNOLOGICAL EVALUATION OF THE EFFECTIVENESS OF INTRAVENOUS IMMUNOGLOBULINS AS AN ADJUVANT THERAPY FOR SURGICAL SEPSIS

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We observed 46 patients with sepsis, which were divided into 2 groups. I group (25 patients) received traditional treatment, II group (21 patients) in addition to conventional therapy received enriched IVIG (IgM+IgA). Comparative assessment of the combination of intravenous immunoglobulin’s and traditional therapy indicated the clinical effectiveness of IVIG therapy, which results in reducing the severity of systemic inflammation, the severity of the disease and the mortality in patients with surgical sepsis.

作者简介

V. Shumatov

State budget educational institute of higher professional education Pacific State MedicalUniversity of Ministry of health Russian Federation

Email: fake@neicon.ru

Doctor of Sciences, Professor of the Department of intensive care, anesthesiology, intensive care and emergency medical services,

Vladivostok

俄罗斯联邦

V. Lazanovich

State budget educational institute of higher professional education Pacific State MedicalUniversity of Ministry of health Russian Federation

编辑信件的主要联系方式.
Email: immuno2003@mail.ru

Ph.D., assistant professor, Department of normal and Pathological Physiology,

 

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V. Krasnikov

State budget educational institute of higher professional education Pacific State MedicalUniversity of Ministry of health Russian Federation

Email: fake@neicon.ru

Ph.D., assistant professor, Department of normal and Pathological Physiology,

Vladivostok

俄罗斯联邦

参考

  1. Busani S., Damiani E., Cavazzuti I. Intravenous immunoglobulin in septic shock: review of the mechanisms of action and meta-analysis of the clinical effectiveness. Minerva Anestesiol. 2016. Vol. 82. P. 559–572.
  2. Шуматов В. Б., Лазанович В. А., Павлов В. А., Ермакова Н. Д., Просекова Е. В. Внутривенные иммуноглобулины в адъювантной терапии сепсиса. Тихоокеанский медицинский журнал, 2017. № 242 С. 42–45.

版权所有 © Shumatov V.B., Lazanovich V.A., Krasnikov V.E., 2019

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