CHARACTERISTICS OF THE INTERFERON SYSTEM AND CELLULAR IMMUNITY OF THE CHILDREN WITH FIRST DIAGNOSED ACTIVE PULMONORY TUBERCULOSIS
- 作者: Sokolova T.1, Mordyk A.1, Shcheglova E.2, Sokol N.2, Aroyan A.1
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隶属关系:
- Omsk State Medical University
- V.P. Bisyarina City Children’s Clinical Hospital № 2
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 554-556
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/120299
- DOI: https://doi.org/10.31857/S102872210006971-3
- ID: 120299
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全文:
详细
The article reveals the features of changes in the system of interferon and cellular immunity, structural and functional organization of the immune system by the number of correlations between its elements among the children with pulmonary tuberculosis. The article gives an analysis of secretion of IFNα and IFNγ, subpopulation composition of blood lymphocytes, communication in the immune system. It is stated that hypo secretion of IFNγ by lymphocytes in vitro with directed induction of cells is registered against the background of a decrease in the number of CD3+, CD4+, CD8+, CD16+, CD20+, HLA-DR+ lymphocytes, an increase in the number of connections between elements of the immune system with a decrease in its mobility.
作者简介
T. Sokolova
Omsk State Medical University
Email: fake@neicon.ru
MD, Prof. at the Department of Pharmacology, Clinical Pharmacology,
Omsk
俄罗斯联邦A. Mordyk
Omsk State Medical University
Email: fake@neicon.ru
MD, Professor, Head of the Department of Phthisiology and Phthisiosurgery,
Omsk
俄罗斯联邦E. Shcheglova
V.P. Bisyarina City Children’s Clinical Hospital № 2
编辑信件的主要联系方式.
Email: eleon_74@mail.ru
PhD, Doctor of clinical immunology laboratories,
Omsk
俄罗斯联邦N. Sokol
V.P. Bisyarina City Children’s Clinical Hospital № 2
Email: fake@neicon.ru
The Head of the of Clinical Laboratory,
Omsk
俄罗斯联邦A. Aroyan
Omsk State Medical University
Email: fake@neicon.ru
Assistant of the Sub-Department of Phthisiology and Phthisiosurgery,
Omsk
俄罗斯联邦参考
- Бердюгина О. В., Мезенцева А. В., Чугаев Ю. П. Особенности иммунологических показателей при туберкулезной инфекции органов дыхания у детей // Современные проблемы науки и образования, 2016. № 2. С. 34.
- Правада Н. C., Серёгина В. А., Будрицкий А. М., Янченко В. В. Значение системы гамма-интерферона и туберкулинсвязывающих моноцитов у пациентов с распространёнными формами туберкулёза лёгких // Современные проблемы здравоохранения и медицинской статистики, 2018, № 2. С. 1–13.
- Писаренко М. С. Особенности секреции интерферона-гамма при лекарственно-устойчивом туберкулезе легких // Фундаментальные исследования, 2013. № 9, ч. 3. С. 444–447.
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