ASSESSMENT OF CORRELATION BETWEEN CYTOKINE STATUS AND RED CELL DISTRIBUTION WIDTH IN PATIENTS WITH ATHEROSCLEROSIS OF LOWER LIMBS AFFECTED BY DIABETES MELLITUS TYPE 2

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Research’s objective is to make an analysis of correlations between index of systemic inflammation and red cell distribution width in patients with diabetes mellitus type 2 aff ected by atherosclerosis of lower limbs. 40 patients with diabetes mellitus were examined. Using Spearmen rank correlation, statistically signifi cant correlations between IL-1β and red cell distribution width were discovered (r=0,358; p=0,027). Herewith there is no signifi cant correlation between IL-6, IL-8, IL-10, TNF-α and red cell distribution width.

作者简介

K. Savchuk

Municipal budgetary healthcare institution city clinic outpatient clinic No 8

编辑信件的主要联系方式.
Email: ksenyasavchuk@gmail.com

chief operating officer,

Chelyabinsk

俄罗斯联邦

L. Ryabova

Federal state budgetary educational institution of higher education “South Ural State Medical University”

Email: fake@neicon.ru

holder of Habilitation degree in medicine, professor of Propaedeutics of Internal Diseases,

Chelyabinsk

俄罗斯联邦

K. Nikushkina

Federal state budgetary educational institution of higher education “South Ural State Medical University”

Email: fake@neicon.ru

senior researcher of Research institute of immunology,

Chelyabinsk

俄罗斯联邦

T. Nikonova

Federal state budgetary educational institution of higher education “South Ural State Medical University”

Email: fake@neicon.ru

senior assistant of Research institute of immunology,

Chelyabinsk

俄罗斯联邦

参考

  1. Тарасов А. А., Резникова Е. А., Давыдов С. И., Бочкарева О. И., Бабаева А. Р. Клиническое и прогностическое значение маркеров эндотелиальной дисфункции при атеросклероз-ассоциированных сосудистых поражениях Медицинский алфавит, 2016, № 30(293), Т. 3., С. 5–11.
  2. Malandrino N., Wu W., Taveira T. Association between red blood cell distribution width and macrovascular and microvascular complications in diabetes. Diabetologia, 2012, 55 (1), 226–235.
  3. de Gonzalo-Calvo D., de Luxan-Delgado B., RodrgiuezGonzalez S. Interleukin 6, soluble tumor necrosis factor receptor I and red blood cell distribution width as biological markers of functional dependence in an elderly population: a translational approach. Cytokine, 2012, 58 (2), 193–198.

版权所有 © Savchuk K.S., Ryabova L.V., Nikushkina K.V., Nikonova T.I., 2019

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