FEATURES CIRCULATING PRO- AND ANTITUMOR MONOCYTES IN PATIENTS WITH TRIPLE NEGATIVE BREAST CANCER
- 作者: Patysheva M.1, Stakheyeva M.1,2, Fedorov A.3, Tarabanovskaya N.1, Grigorieva E.1, Slonimskaya E.1, Kzhyshkowska J.4, Cherdyntseva N.1,2
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隶属关系:
- Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences
- Tomsk State University
- Siberian State Medical University
- ФГАОУ ВО «Национальный исследовательский Томский государственный университет»
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 459-461
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/120259
- DOI: https://doi.org/10.31857/S102872210006929-6
- ID: 120259
如何引用文章
全文:
详细
Phenotypic markers of pro- and antitumor polarization of blood monocytes in patients with a triple negative breast cancer were characterized in this work. This molecular subtype differed from the luminal B and Her2+ subtypes in the content of CD163+, stabilized-1+ and HLA-DR+ circulating monocytes. The identified differences can be used as a differential diagnostic marker for a triple negative breast cancer subtype.
作者简介
M. Patysheva
Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences
编辑信件的主要联系方式.
Email: starin5@yandex.ru
MD, Clinical Laboratory Scientist of Cancer Research Institute,
Tomsk
俄罗斯联邦M. Stakheyeva
Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences;Tomsk State University
Email: fake@neicon.ru
PhD, Leading Researcher of Cancer Research Institute,
Tomsk
俄罗斯联邦A. Fedorov
Siberian State Medical University
Email: fake@neicon.ru
student,
Tomsk
俄罗斯联邦N. Tarabanovskaya
Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences
Email: fake@neicon.ru
MD, PhD, Researcher of Cancer Research Institute,
Tomsk
俄罗斯联邦E. Grigorieva
Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences
Email: fake@neicon.ru
PhD, Junior Researcher of Cancer Research Institute,
Tomsk
俄罗斯联邦E. Slonimskaya
Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences
Email: fake@neicon.ru
MD, PhD, Head of the general oncology,
Tomsk
俄罗斯联邦J. Kzhyshkowska
ФГАОУ ВО «Национальный исследовательский Томский государственный университет»
Email: fake@neicon.ru
PhD, Professor of Tomsk State University, the Head of the laboratory of translational cellular and molecular biomedicine,
Tomsk
俄罗斯联邦N. Cherdyntseva
Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences;Tomsk State University
Email: fake@neicon.ru
PhD, Head of the laboratory of molecular oncology and immunology;
the Leading Researcher of laboratory of translational cellular and molecular biomedicine,
Tomsk
俄罗斯联邦参考
- Bianchini G., Balko J. M., Mayer I. A., Sanders M. E., Gianni L. Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease. Nat Rev Clin Oncol. 2016 Nov;13(11):674–690.
- Zhang B., Cao M., He Y., Liu Y., Zhang G., Yang C., Du Y., Xu J., Hu J., Gao F. Increased circulating M2- like monocytes in patients with breast cancer. Tumour Biol. 2017; 39(6):1010428317711571.
