THE ROLE OF CERTAIN BLOOD CYTOKINES AND FACTORS OF INNATE IMMUNITY FOR PREDICTION OF REACTIVE ARTHRITIS OUTCOME

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The clinical and immunological examination of children with reactive arthritis (ReA) and discriminant analysis allowed to establish significant serum factors associated with the clinical variant of ReA (IL-17, IL-6, INF-γ, lysozyme, CRP), which indicates a possible Use them as markers for predicting the clinical course of ReA and the outcome of arthritis.

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O. Chelpachenko

Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences

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E. Danilova

Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences

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I. Nikiforov

Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences

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L. Fedotova

Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences

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参考

  1. Scher J. U. Microbiome in inflammatory arthritis and human rheumatic diseases / J. U. Scher, D. R. Littman, S. B. Abramson // Arthritis Rheumatol.- 2016.- Vol.68, N.1.- P. 35-45.
  2. Sieper J. Pathogenesis of reactive arthritis / J. Sieper // Curr Rheumatol Rep.- 2001.- N. 3.- P. 412-418.
  3. Rosenbaum J. T. The microbiome: A revolution in treatment for rheumatic diseases? / J. T. Rosenbaum, M. J. Asquith // Curr. Rheumatol. Rep.- 2016.- N. 18.- P. 62.
  4. Elevated levels of serum MRP8/14 in ankylosing spondylitis: Associated with peripheral arthritis and active disease / L. Gupta, S. Bhattacharya, V. Ag-garwal et al. // Clin. Rheumatol.- 2016.- Vol. 35, N.12.- P. 3075-3079.

版权所有 © Chelpachenko O.E., Danilova E.I., Nikiforov I.A., Fedotova L.P., 2017

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