IMMUNOENDOCRINE DISTURBANCES IN PATIENTS WITH SCHIZOPHRENIA IN THE PROCESS OF ANTIPSYCHOTIC THERAPY
- 作者: Lobacheva O.1, Vetlugina T.1, Kornetova E.1, Semke A.1
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隶属关系:
- Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences (Mental Health Research Institute of Tomsk NRMC)
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 374-376
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/120020
- DOI: https://doi.org/10.31857/S102872210006632-0
- ID: 120020
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详细
Study of dynamics of immunoendocrine parameters in 27 patients with schizophrenia has shown that acute period of schizophrenia after long-term maintenance treatment with quetiapine is accompanied by immune-hormonal imbalance characterized by cellular immune deficit, increase in the concentration thyroid-stimulating hormone, reduction in thyroid hormones and prolonged elevation of the level of cortisol in blood. The obtained data will allow further revealing the criteria of personalized approach to treatment of patients with possible joining additional pharmacotherapy from the first days of the admission of patients in the hospital.
作者简介
O. Lobacheva
Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences (Mental Health Research Institute of Tomsk NRMC)
编辑信件的主要联系方式.
Email: oalobacheva@mail.ru
MD, lead researcher of the Laboratory of Clinical Psychoneuroimmunology and Neurobiology,
Tomsk
俄罗斯联邦T. Vetlugina
Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences (Mental Health Research Institute of Tomsk NRMC)
Email: fake@neicon.ru
D. Sc., Prof., lead researcher of the Laboratory of Clinical Psychoneuroimmunology and Neurobiology, Head of the Department of Biological Psychiatry and Narcology,
Tomsk
俄罗斯联邦E. Kornetova
Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences (Mental Health Research Institute of Tomsk NRMC)
Email: fake@neicon.ru
MD., lead researcher of the Endogenous Disorders Department,
Tomsk
俄罗斯联邦A. Semke
Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences (Mental Health Research Institute of Tomsk NRMC)
Email: fake@neicon.ru
MD., Prof., Head of the Endogenous Disorders Department,
Tomsk
俄罗斯联邦参考
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- Мосолов С. Н., Цукарзи Э. Э., Капилетти С. Г. Антипсихотическая фармакотерапия шизофрении: от научных данных к клиническим рекомендациям. В кн.: Биологические методы терапии психических расстройств / Ред. Мосолов С. Н. Доказательная медицина – клинической практике. Москва, 2012, 11–61.
- Ветлугина Т. П., Лобачева О. А., Альперина Е. Л., Жукова Е. Н., Семке А. В., Никитина В. Б., Чейдо М. А., Идова Г. В. Клинико-экспериментальные исследования иммуномодулирующего эффекта амисульприда. Вестник Российской академии медицинских наук. 2012, 12(67), 13–17.
