CYTOKINE PROFILE OF NEWBORN CHILDREN WITH GENERALIZED HERPETIC INFECTION
- 作者: Levkovich M.1, Kravchenko L.1, Levkovich A.1,2, Pyatikova M.1
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隶属关系:
- Rostov State Medical University, Ministry of Health of Russia
- Regional Clinical Hospital № 2
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 368-370
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/120001
- DOI: https://doi.org/10.31857/S102872210006630-8
- ID: 120001
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全文:
详细
New data confirming the role of immune system disorders in the pathogenesis of generalized herpes infection are presented. It has been established that in newborns the development of generalized herpes virus infection is associated with impaired cytokine balance, with a tendency to T2 directional type of immune response, insufficiency of IFNα and IFNγ production.
作者简介
M. Levkovich
Rostov State Medical University, Ministry of Health of Russia
编辑信件的主要联系方式.
Email: xlma@mail.ru
Doctor of Medical Sciences, Associate Professor, Leading Researcher of the Department of Biomedical Problems in Obstetrics, Gynecology and Pediatrics,
Rostov-on-Don
俄罗斯联邦L. Kravchenko
Rostov State Medical University, Ministry of Health of Russia
Email: fake@neicon.ru
doctor of medical sciences, associate professor, leading researcher of the pediatric department,
Rostov-on-Don
俄罗斯联邦A. Levkovich
Rostov State Medical University, Ministry of Health of Russia;Regional Clinical Hospital № 2
Email: fake@neicon.ru
Candidate of Medical Sciences, head. Department of Newborns,
Rostov-on-Don
俄罗斯联邦M. Pyatikova
Rostov State Medical University, Ministry of Health of Russia
Email: fake@neicon.ru
pediatrician of the department of young children,
Rostov-on-Don
俄罗斯联邦参考
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- Gantt S. and Muller W. J. The Immunologic Basis for Severe Neonatal Herpes Disease and Potential Strategies for Therapeutic Intervention. Clin Dev Immunol. 2013,1–16.
- Кравченко Л. В., Левкович М. А. Механизмы иммуносупрессии при частых острых респираторновирусных инфекциях у детей, перенесших цитомегаловирусную инфекцию в периоде новорожденности. ВИЧ-инфекция и иммуносупрессии. 2017, 9(3), 34–38.
- Левкович М. А., Афонин А. А., Кравченко Л. В., Левкович А. Ю., Демидова М. В., Заурова Л. М. Показатели иммунного статуса и функциональной активности лимфоцитов у новорожденных детей с герпесвирусной инфекцией. Российский аллергологический журнал. 2013, 2–2, 174–175.
- Кравченко Л. В., Левкович М. А., Пятикова М. В. Роль полиморфизма гена интерферона γ и интерферонопродукции в патогенезе инфекции, вызванной вирусом герпеса 6 типа у детей раннего возраста. Клиническая лабораторная диагностика. 2018, 63(6), 357–361.
