Immune biomarkers of in-stent restenosis after percutaneous coronary interventions in myocardial infarction and stable angina patients
- 作者: Grachev N.1, Semenikhin A.1, Turmova E.1, Rublev V.2, Nazarenko S.2, Anohina N.2
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隶属关系:
- Pacific State Medical University
- Primorye Regional Clinical Hospital № 1
- 期: 卷 21, 编号 3 (2018)
- 页面: 255-260
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/119849
- DOI: https://doi.org/10.31857/S102872210002391-5
- ID: 119849
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详细
The study was aimed to assess the prognostic role of infl ammation biomarkers to evaluate the risk for restenosis in myocardial infarction and stable angina patients undergoing percutaneous coronary intervention. The blood samples were tested immediately before and 7 days after percutaneous coronary intervention for IFN-γ, IL-6, IL-8, IL-17, TNF-α, TNF-β, TGF-β1 and TGF-β2. The key predictors of restenosis after percutaneous coronary intervention during one year were abnormal rates of IFN-γ pre-PCI (OR=5,21) and 7 days after (OR=3,84), IL-6 pre-PCI (OR=1,59), IL-8 pre-PCI (OR=1,73), IL-17 pre- PCI (OR=3,07) and 7 days after (OR=2,34), TNF-α pre-PCI (OR=1,88), TNF-β pre-PCI (OR=1,98) and growth factors: TGF-β1 7 days after PCI (OR=1,82) and TGF-β2 7 days after PCI (OR=2,04).
作者简介
N. Grachev
Pacific State Medical University
编辑信件的主要联系方式.
Email: noemail@neicon.ru
俄罗斯联邦
A. Semenikhin
Pacific State Medical University
Email: noemail@neicon.ru
俄罗斯联邦
E. Turmova
Pacific State Medical University
Email: noemail@neicon.ru
俄罗斯联邦
V. Rublev
Primorye Regional Clinical Hospital № 1
Email: noemail@neicon.ru
俄罗斯联邦
S. Nazarenko
Primorye Regional Clinical Hospital № 1
Email: noemail@neicon.ru
俄罗斯联邦
N. Anohina
Primorye Regional Clinical Hospital № 1
Email: noemail@neicon.ru
俄罗斯联邦
参考
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