FEATURES OF T-LYMPHOCYTES SUBPOPULATIONS IN CHRONIC HERPETIC INFECTION

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The one of the most signifi cant factor of immunosuppression is chronic herpetic infection. The absence of vaccine and unclear knowledge about reactivation`s pathogenesis also emphasize the importance of additional immune response study. We research the level of T-cell subpopulations during chronic herpetic infection. Treg percentage in main group was exceed one`s level in healthy control group. Also the signifi cant increasing of Th1\Th2 index was examined.

作者简介

S. Knysh

Federal State Budget Educational Institution of Higher Education «Pacific state medical university» Ministry of Health Russia

编辑信件的主要联系方式.
Email: immunolog.vl@gmail.com

assistant professor of normal and pathological physiology department,

Vladivostok

俄罗斯联邦

V. Malkov

Federal State Budget Educational Institution of Higher Education «Pacific state medical university» Ministry of Health Russia

Email: fake@neicon.ru

assistant professor of normal and pathological physiology department,

Vladivostok

俄罗斯联邦

A. Shiraeva

Federal State Budget Educational Institution of Higher Education «Pacific state medical university» Ministry of Health Russia

Email: fake@neicon.ru

student of medical faculty, 

Vladivostok

俄罗斯联邦

E. Baibarina

«Center Vrachebnoi Cosmetologii»

Email: fake@neicon.ru

dermatologist, company director,

Voronezh

俄罗斯联邦

参考

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  3. Penaloza-MacMaster P., Kamphorst A. O., Wieland A., Araki K., Iyer S. S., West E. E., O’Mara L., Yang S., Konieczny B. T., Sharpe A. H., Freeman G. J., Rudensky A. Y., Ahmed R. Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection. The Journal of experimental medicine. 2014, 211(9), 1905–18.
  4. Takahashi R., Sato Y., Kurata M., Yamazaki Y., Kimishima M., Shiohara T. Pathological Role of Regulatory T Cells in the Initiation and Maintenance of Eczema Herpeticum Lesions. The Journal of Immunology. 2014, 192 (3), 969–978.
  5. Vukmanovic-Stejic M., Sandhu D., Seidel J. A., Patel N., Sobande T. O., Agius E., Jackson S. E., Fuentes-Duculan J., Suárez-Fariñas M., Mabbott N. A., Lacy K. E., Ogg G., Nestle F. O., Krueger J. G., Rustin M., Akbar A. N. The Characterization of Varicella Zoster Virus-Specifi c T Cells in Skin and Blood during Aging. The Journal of investigative dermatology. 2015, 135(7), 1752–1762.

版权所有 © Knysh S.V., Malkov V.A., Shiraeva A.V., Baibarina E.V., 2019

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此作品已接受知识共享署名 4.0国际许可协议的许可
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