ANALYSIS OF PHAGOCYTIC ACTIVITY OF NEUTROPHILS DURING ATHEROSCLEROSIS
- 作者: Kilinа O.1, Dutova S.1, Saranchina Y.1, Matrosova T.1, Pol’shcha N.1, Kulakova T.1, Chanarin N.1, Shandakov P.2
-
隶属关系:
- Khakass state University named after N. F. Katanov
- Republican clinical hospital named after G. YA. Remishevskaya
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 299-301
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/119807
- DOI: https://doi.org/10.31857/S102872210006607-2
- ID: 119807
如何引用文章
全文:
详细
The article presents the results of a comparative analysis of phagocytic activity of neutrophils, isolated from explants of atherosclerotic plaques obtained during endarterectomy in patients with atherosclerosis of the brachiocephalic and femoral arteries and peripheral blood neutrophils of the same patients. Phagocytic activity of neutrophils in atherosclerotic plaques was found to be statistically significantly reduced. We assume that the depletion of the functional ability of neutrophils in the composition of atherosclerotic plaques is associated with chronic inflammation in the intima of vessels in atherosclerosis.
作者简介
O. Kilinа
Khakass state University named after N. F. Katanov
编辑信件的主要联系方式.
Email: fake@neicon.ru
doctor of medical Sciences, Director of Medical-psychological-social Institute, Professor of the Department of internal diseases,
Abakan
俄罗斯联邦S. Dutova
Khakass state University named after N. F. Katanov
Email: fake@neicon.ru
doctor of science, associate Professor, acting head of the Department of fundamental medicine and hygiene of Medical, psychological and social Institute,
Abakan
俄罗斯联邦Yu. Saranchina
Khakass state University named after N. F. Katanov
Email: fake@neicon.ru
PhD, associate Professor of the Department of fundamental medicine and hygiene,
Abakan
俄罗斯联邦T. Matrosova
Khakass state University named after N. F. Katanov
Email: fake@neicon.ru
student of Medical-psychological-social Institute,
Abakan
俄罗斯联邦N. Pol’shcha
Khakass state University named after N. F. Katanov
Email: fake@neicon.ru
associate Professor in the Department of internal diseases,
Abakan
俄罗斯联邦T. Kulakova
Khakass state University named after N. F. Katanov
Email: fake@neicon.ru
post-graduate student of the Department of General professional disciplines,
Abakan
俄罗斯联邦N. Chanarin
Khakass state University named after N. F. Katanov
Email: fake@neicon.ru
PhD, associate Professor of the Department of General professional disciplines,
Abakan
俄罗斯联邦P. Shandakov
Republican clinical hospital named after G. YA. Remishevskaya
Email: fake@neicon.ru
PhD, head of the Department of vascular surgery,
Abakan
俄罗斯联邦参考
- Weber C, Zernecke A, Libby P. The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models. Nat Rev Immunol, 2008, 8, 802–815.
- Xue-Mei L, Jie Ch, Dai Xuan, Xiao-Xing L, ChunLin H, Yu-Jie L. Changes in CD4+CD25+ Tregs in the pathogenesis of atherosclerosis in ApoE-/- mice. Exp Biol Med (Maywood), 2017, 242(9), 918–925.
- Sivalingam Z., Larsen S. B., Grove E. L., Hvas A. M., Kristensen S.D., Magnusson N. E. Neutrophil gelatinase-associated lipocalin as a risk marker in cardiovascular disease(Review). Clinical Chemistry and Laboratory Medicine, 2017, 56(1), 5–18.
- Pertiwi K.R., van der Wal A.C., Pabittei D.R., Mackaaij C., van Leeuwen M.B., Li X, de Boer O. J. Neutrophil кxtracellular traps participate in all different types of thrombotic and haemorrhagic complications of coronary atherosclerosis. Thrombosis and Haemostasis, 2018, 118(6), 1078–87. 5. Hoyer F. F., Nahrendorf M. Neutrophil contributions to ischaemic heart disease. Eur Heart J, 2017, 3, 465–472.
