INFLUENCY OF INFLUENCES OF REGULATORY PEPTIDES AND RECOMBINANT IFNα ON THE PHENOTYPE OF THE SUBSET CD66b+CD33+CD16+CD11b+NEUTROFIL GRANULOCYTES IN VITRO

I. V. Nesterova; Нестерова И. В.; G. A. Chudilova; Чудилова Г. А.; S. V. Kovaleva; Ковалева С. В.; L. V. Lomtatidze; Ломтатидзе Л. В.; T. V. Rusinova; Русинова Т. В.; V. A. Tarakanov; Тараканов В. А.; N. K. Barova; Барова Н. К.; V. N. Pavlenko; Павленко В. Н.

doi:10.31857/S102872210006645-4

INFLUENCY OF INFLUENCES OF REGULATORY PEPTIDES AND RECOMBINANT IFNα ON THE PHENOTYPE OF THE SUBSET CD66b+CD33+CD16+CD11b+NEUTROFIL GRANULOCYTES IN VITRO

作者: Nesterova I.V.¹^,2, Chudilova G.A.¹, Kovaleva S.V.¹, Lomtatidze L.V.¹, Rusinova T.V.¹, Tarakanov V.A.¹, Barova N.K.¹, Pavlenko V.N.¹
隶属关系:
1. Kuban State Medical University
2. Peoples’ Friendship University of Russia
期: 卷 22, 编号 2-2 (2019)
页面: 867-869
栏目: ORIGINAL ARTICLES
URL: https://journals.rcsi.science/1028-7221/article/view/119786
DOI: https://doi.org/10.31857/S102872210006645-4
ID: 119786

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详细

A model of the bacterial process under the influence of fMLP was reproduced in the in vitro system, which made it possible to reveal the features of the transformation of CD66b⁺CD33⁺CD16⁺CD11b⁺neutrofi l granulocytes (NG). Multidirectional effects of mono-effects of peptides and rIFNα2b on the expression of the studied markers of NG in healthy children were identified. The modulating effect of rIFNα2b on the transformed fMLP phenotype of NG is associated with polarization into an anti-inflammatory phenotype.

关键词

neutrophilic granulocytes, phenotype, subset

作者简介

I. Nesterova

Kuban State Medical University;
Peoples’ Friendship University of Russia

编辑信件的主要联系方式.
Email: inesterova1@yandex.ru

Chief Researcher, Central Research Laboratory;

MD, Professor, Department of Allergology and Immunology,

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