COMPARATIVE CHARACTERISTICS OF THE SUBPOPULATION COMPOSITION OF LYMPHOCYTES AND HEAT SHOCK PROTEIN IN PATIENTS WITH VIBRATION DISEASE
- 作者: Kurchevenko S.1, Bodienkova G.1,2, Lakhman O.1
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隶属关系:
- FSBI “East-Siberian Institute of Medical and Ecological Research”
- Irkutsk National Research Technical University
- 期: 卷 22, 编号 2-2 (2019)
- 页面: 846-848
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/119739
- DOI: https://doi.org/10.31857/S102872210006677-9
- ID: 119739
如何引用文章
全文:
详细
Comparative analysis of the subpopulations of lymphocytes in patients with vibration disease (VB) from the effects of local vibration revealed the features of the immune response, characterized by increasing the absolute amount of CD3+-, CD4+-, CD8+- lymphocytes and decreased the percentage of CD20+-, CD25+-lymphocytes. In patients with VB from the effects of combined vibration, an increase in the absolute number of CD3+-, CD4+ -, CD8+ -, CD16+ -, CD20+-, CD25+-, CD95+-lymphocytes was observed, which indicates the activation of lymphocyte apoptosis under conditions of pronounced stimulation of the immune system. A decrease in the level of HSP70 in the serum of patients with VB from exposure to local vibration indicates its accumulation inside the cell and the protection of the processes of biosynthesis and the structural integrity of proteins in the damaged cell due to B-lymphocytes.
作者简介
S. Kurchevenko
FSBI “East-Siberian Institute of Medical and Ecological Research”
编辑信件的主要联系方式.
Email: immun11@yandex.ru
PhD, Researcher of the laboratories of Immune and biochemical and molecular and genetic research,
Angarsk
俄罗斯联邦G. Bodienkova
FSBI “East-Siberian Institute of Medical and Ecological Research”;Irkutsk National Research Technical University
Email: fake@neicon.ru
DMS, Professor, Head of the Laboratories of Immune and biochemical and molecular and genetic research, Angarsk;
Professor, Department of Industrial Ecology and Safety of Vital Functions, Irkutsk
俄罗斯联邦O. Lakhman
FSBI “East-Siberian Institute of Medical and Ecological Research”
Email: fake@neicon.ru
Professor of the Russian Academy of Sciences, DMS, Professor, Director,
Angarsk
俄罗斯联邦参考
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- Bodienkova G. M., Kurchevenko S. The relationship between the cytokine concentrations and levels of antibodies to neuronal proteins in workers who were exposed to vibration. Neurochemical Journal. 2016, 33; 1, 85–89.
- Потапнев М. П. Аутофагия, апоптоз, некроз, клеток и иммунное распознавание своего и чужого. Иммунология. 2014, 35; 2, 95–102.
- Yasuyuki A., Takayoshi J. and Tomohiko O. Oral Treponemes and their outer membrane extracts activate human gingival epithelial cells through toll like receptor 2. Infection and Immunity. 2003, 71; 2, 717–725.
