ASSESSMENT OF HIGH LEVELS OF ANTIBODIES TO HERPES SIMPLEX VIRUS CLINICAL VALUE IN HEAD AND BACK PAIN OUTPATIENTS

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Aim: to assess clinical value of antibodies to Herpes Simplex Virus (HSV) in outpatients with head and back pain. Cross sectional study included 45 female outpatients aged from 40 to 60. Two or more HSVinfec-tion exacerbations per year were registered in 25 persons (Group1) while 20 women had no exacerbation during previous year (Group 2). General practitioner and neurologist examination have been performed accompanied by IEA IgG anti-HSV type 1,2 antibodies assessment. Results: Group 1 showed 5-fold higher IgG anti-HSV antibodies level and post-herpetic neuralgia frequency then Group 2. High IgG anti-HSV antibodies level was associated with increased odds of HSV infection exacerbation (OR = 1.8; 95 % СШ 1.2-2.6).

作者简介

I. Nokhrina

Central City Clinical Hospital № 6

编辑信件的主要联系方式.
Email: noemail@neicon.ru
俄罗斯联邦

A. Popov

Central City Clinical Hospital № 6

Email: noemail@neicon.ru
俄罗斯联邦

I. Tuzankina

Institute of Immunology and Physiology

Email: noemail@neicon.ru
俄罗斯联邦

参考

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  2. Lee S., Ives A.M., Bertke A.S. Herpes Simplex Virus 1 Reactivates from Autonomic Ciliary Ganglia Independently from Sensory Trigeminal Ganglia To Cause Recurrent Ocular Disease. Hutt-Fletcher L, ed. Journal of Virology. 2015;89(16):8383-8391. doi: 10.1128/JVI.00468-15.
  3. Никитин К. А., Алексеева Д. А., Паникаров-ская М. М. Поражение тройничного нерва при герпетической инфекции в оториноларингологии. Вестник оториноларингологии. 2016. Т. 81. № 4. С. 19-21 (Nikitin K.A., Alekseeva D.A., Panikarovskaya M.M. The damage to the trigeminal nerve associated with herpeic viral infraction in otorhinolagygology. Vestn Otorinolaringol. 2016;81(4):19-21. Russian.)
  4. Xu L., Zhang Y., Huang Y. Advances in the Treatment of Neuropathic Pain. Adv Exp Med Biol. 2016;904:117-129. doi: 10.1007/978-94-017-7537-3

版权所有 © Nokhrina I.N., Popov A.A., Tuzankina I.A., 2017

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