REACTION OF CELLULAR FACTORS IN INNATE AND ADAPTIVE IMMUNITY OF THE PIGLETS ON THE INTRODUCTION OF THE DRUG «ANANDIN»

The purpose of this study is to study the eff ect of the drug “Anandin” on some cellular factors of innate and adaptive immunity in piglets. “Anandin” is a drug from the group of immunomodulators that contains two types of compounds, these are derivatives of acridone acetic acid, as well as nitrogencontaining a-D-glucofurase. For the experiment, 30 piglets were selected 15 days before weaning (40 days old). The mass and physiological state of the animals was the same. The study involved a single administration of 10% solution “Anandin” experimental group of animals at a dose of 15 mg/kg body weight. The control group was intact. Before and after the introduction of the drug were carried out laboratory blood tests. The results showed that “Anandin” has a positive eff ect on the performance of cellular factors of immunity. The parameters studied: the activity of oxygen-dependent and oxygen-independent bactericidal systems of neutrophils (LKT and NBT-stimulated), production of lymphokines in RTML, removal of antigens (level of circulating immune complexes).

innate immunity, adaptive immunity, cellular factors, “Anandin”, pigs