THE STUDY OF THE FUNCTIONAL CHARACTERISTICS OF NEUTROPHILIC GRANULOCYTES WHEN EXPOSED TO IRON-CONTAINING NANOPARTICLES FERRIHYDRITE
- 作者: Kolenchukova O.1,2, Stolyar S.3,2, Ladynina L.3
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隶属关系:
- Research Institute of Medical Problems of the North, Federal Research Centre «Krasnoyarsk Research Centre», Siberian Division of the Russian Academy of Sciences
- Siberian Federal University
- L.V. Kirensky Institute of Physics, Federal Research Centre «Krasnoyarsk Research Centre», Siberian Division of the Russian Academy of Sciences
- 期: 卷 22, 编号 2-2 (2019)
- 页面: 801-803
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/119620
- DOI: https://doi.org/10.31857/S102872210006693-7
- ID: 119620
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全文:
详细
The study is devoted to determining the effect of magnetic iron-containing nanoparticles on the functional state of blood neutrophils. The object of the study was neutrophil granulocytes (n=34). 3 groups were formed: control (without incubation); in the second group – exposed to synthetic magnetic ironcontaining ferrihydrite nanoparticles; in the third group – synthetic magnetic iron-containing ferrihydrite nanoparticles, in the third group – synthetic magnetic iron-containing ferrihydrite nanoparticles coated with natural polysaccharide – arabinogalactane. The concentration of nanoparticles ferrihydrite was 5 mg/ml and 20 mg/ml. Explored the early and late chemiluminescent response. It was found that the functional activity of cells under the influence of different experimental types of iron-containing nanoparticles varies depending on the concentration, with an increase in the number of acting nanoparticles, a unidirectional reaction with a decrease in cell activity is observed.
作者简介
O. Kolenchukova
Research Institute of Medical Problems of the North, Federal Research Centre «Krasnoyarsk Research Centre», Siberian Division of the Russian Academy of Sciences;Siberian Federal University
编辑信件的主要联系方式.
Email: Kalina-chyikova@mail.ru
MD, PhD, researcher,
660022 Krasnoyarsk, Partizana Zelezniakast. 3G
俄罗斯联邦S. Stolyar
L.V. Kirensky Institute of Physics, Federal Research Centre «Krasnoyarsk Research Centre», Siberian Division of the Russian Academy of Sciences;Siberian Federal University
Email: fake@neicon.ru
MD, PhD, researcher,
Krasnoyarsk
俄罗斯联邦L. Ladynina
L.V. Kirensky Institute of Physics, Federal Research Centre «Krasnoyarsk Research Centre», Siberian Division of the Russian Academy of Sciences
Email: fake@neicon.ru
researcher,
Krasnoyarsk
俄罗斯联邦参考
- Balaev D. A., Dubrovskii A. A., Bayukov O. A., Stolyar S. V., Iskhakov R. S., Krasikov A. A., Yaroslavtsev R. N., Ladygina V. P. The effect of low-temperature heat treatment on the magnetic properties of biogenic ferrihydrite nanoparticles. Technical Physics Letters. 2015, 41(7), 705–709.
- Balaev D. A., Dubrovskii A. A., Semenov S. V., Bayukov O. A., Stolyar S. V., Iskhakov R. S., Krasikov A. A., Ishchenko L. A., Ladygina V. P. Magnetic properties and the mechanism of formation of the uncompensated magnetic moment of antiferromagnetic ferrihydrite nanoparticles of a bacterial origin // Journal of Experimental and Theoretical Physics. 2014, 119(3), 479–487.
- Iskhakov R. S., Chekanova L. A., Stolyar S. V., Vazhenina I. G. Spin-wave resonance in multilayer fenip/pd films // Bulletin of the Russian Academy of Sciences: Physics. 2014, 78(4), 328–329.