MUTATIONS IN THE GENES OF T-CELL RECEPTOR AND THE FUNCTIONAL STATE OF THE IMMUNE SYSTEM IN IRRADIATED PERSONS
- 作者: Akleyev A.1,2, Blinova E.2,3, Dolgushin I.1
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隶属关系:
- Southern-Urals State Medical University of the RF Ministry of Public Health
- Urals Research Center for Radiation Medicine of the FMBA of Russia
- Chelyabinsk State University
- 期: 卷 20, 编号 3 (2017)
- 页面: 357-358
- 栏目: Articles
- URL: https://journals.rcsi.science/1028-7221/article/view/119527
- ID: 119527
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详细
Among the exposed persons with elevated levels of TCR-mutations increase in levels of NK-CTL, activation of lysosomal activity of neutrophils, increase of serum ^-1α with depression of IL-2 and GM-CSF were observed.
作者简介
A. Akleyev
Southern-Urals State Medical University of the RF Ministry of Public Health; Urals Research Center for Radiation Medicine of the FMBA of Russia
编辑信件的主要联系方式.
Email: noemail@neicon.ru
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E. Blinova
Urals Research Center for Radiation Medicine of the FMBA of Russia; Chelyabinsk State University
Email: noemail@neicon.ru
俄罗斯联邦
I. Dolgushin
Southern-Urals State Medical University of the RF Ministry of Public Health
Email: noemail@neicon.ru
俄罗斯联邦
参考
- I. ICRP Publication 118. Early and late effects of radiation in normal tissues and organs - threshold doses for tissue reactions in a radiation protection context. Annals of the ICRP. Elsevier. 2012, 322 p.
- Смирнова С. Г., Орлова Н. В., Замулаева И. А., Саенко А. С. Мутации по локусу Т-клеточного рецептора у людей в отдалённые сроки после острого и пролонгированного облучения. Радиационная биология. Радиоэкология. 2002, 42 (6), 624-627.
- Blinova E. A., Veremyeva G. A., Akleyev A. V. Apoptosis of peripheral blood lymphocytes and mutations in the gene of the T-cell receptor in survivors of chronic radiation exposure. Health Physics. 2012, V. 3, No. 1., 58-60.
