ANALYSIS OF IMMUNOLOGICAL INDEXES AND EXTERNAL BREATH FUNCTION IN PATIENTS WITH BRONCHIAL ASTHMA UNDER THE TREATMENT WITH T-CELL IMMUNOTHERAPY AND STANDARD THERAPY
- 作者: Blinova E.1, Makarova A.1, Pashkina E.1, Demina D.1, Kozlov V.1
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隶属关系:
- Federal State Budgetary Scientific Institution «Research Institute of Fundamental and Clinical Immunology»
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 168-170
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/119461
- DOI: https://doi.org/10.31857/S102872210006438-6
- ID: 119461
如何引用文章
全文:
详细
The study presents the clinical and immunological characteristics of patients with bronchial asthma, which had administrated with standard therapy and T-cell immunotherapy. After cell therapy, it was shown an improvement of external breath function, an increase in the number of CD8+ lymphocytes, a decrease in CD19+ cell subset, as well as a reducing of IgE level in the atopic form of the disease. All together it indicates the eff ectiveness of cell therapy. In patients with standard therapy, there was no change of investigated parameters in dynamics.
作者简介
E. Blinova
Federal State Budgetary Scientific Institution «Research Institute of Fundamental and Clinical Immunology»
编辑信件的主要联系方式.
Email: blinovaelena-85@yandex.ru
PhD, senior researcher of the Laboratory of Clinical immunopathology,
Novosibirsk
俄罗斯联邦A. Makarova
Federal State Budgetary Scientific Institution «Research Institute of Fundamental and Clinical Immunology»
Email: fake@neicon.ru
vaccinologist of Clinic of immunopathology,
Novosibirsk
俄罗斯联邦E. Pashkina
Federal State Budgetary Scientific Institution «Research Institute of Fundamental and Clinical Immunology»
Email: fake@neicon.ru
PhD, researcher of the Laboratory of Clinical immunopathology,
Novosibirsk
俄罗斯联邦D. Demina
Federal State Budgetary Scientific Institution «Research Institute of Fundamental and Clinical Immunology»
Email: fake@neicon.ru
Head of the allergology department of Clinical immunopathology,
Novosibirsk
俄罗斯联邦V. Kozlov
Federal State Budgetary Scientific Institution «Research Institute of Fundamental and Clinical Immunology»
Email: fake@neicon.ru
academic RAS, M.D. D.S., Head of the Laboratory of Clinical immunopathology, scientific adviser,
Novosibirsk
俄罗斯联邦参考
- Global Strategy for Asthma Management and Prevention (GINA) 2015. – www.ginasthma.com.
- Патент RU № 2652752 C1. Блинова Е. А., Пашкина Е. А., Тевс А. Е., Непомнящих В. М., Леонова М. И., Демина Д. В., Козлов В. А. «Способ лечения бронхиальной астмы» // опубликован 28.04.2018 г. Бюллетень № 13.
- Скибо Ю. В., Курмаева Н. Ш., Цибулькина В. Н., Абрамова З. И. Структура основных популяций лимфоцитов у больных атопической бронхиальной астмой разной степени тяжести // Практическая медицина. 2012. – № 9 (65). – С. 154–158.
