HIV INFECTION AND HIV/HCV CO-INFECTION PROBLEM

The patterns of coinfection, which extend to coinfection of HIV/HCV, make it expedient to test the hypothesis about the impact of the order of viral pathogens admission into host for the development of the infectious process. It was found that this factor has a significant impact on the course of liver fibrosis, the viral load of HIV and HCV, the state of the immune response. In cases where HIV infection develops before hepatitis C virus infection, liver fibrosis often takes a progressive course, the viral load of HIV is reduced, and HCV load increases, CD8+ T-lymphocytes and immunoregulatory index values become lower.