INFLUENCE OF MILIACIN TRITERPENOID ON ANTILYSOCIMATIC ACTIVITY OF MICROORGANISMS
- Authors: Filippova Y.V.1, Bondarenko T.A.2, Panfilova T.V.1, Zheleznova A.D.1, Sarycheva Y.A.1, Tokareva A.A.1
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Affiliations:
- Orenburg State Medical University, Ministry of Health of the Russian Federation
- FGBUN Institute for Cellular and Intracellular Symbiosis
- Issue: Vol 22, No 2-1 (2019)
- Pages: 602-604
- Section: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/120315
- DOI: https://doi.org/10.31857/S102872210007013-9
- ID: 120315
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Abstract
The inhibitory effect of triterpenoid miliacin in a dose of 50 μg / ml on the persistent trait of microorganisms – antilysocyme activity was established. The revealed property of militia along with its immunomodulating activity can provide a previously identified protective effect in experimental Salmonella infection.
About the authors
Y. V. Filippova
Orenburg State Medical University, Ministry of Health of the Russian Federation
Author for correspondence.
Email: probllab.orenburg@mail.ru
Ph.D., Researcher, Problem Research Laboratory,
Orenburg
Russian FederationT. A. Bondarenko
FGBUN Institute for Cellular and Intracellular Symbiosis
Researcher, Laboratory of Biomonitoring and Molecular Genetic Research,
Orenburg
Russian FederationT. V. Panfilova
Orenburg State Medical University, Ministry of Health of the Russian Federation
PhD, Associate Professor, Department of Pathological Physiology,
Orenburg
Russian FederationA. D. Zheleznova
Orenburg State Medical University, Ministry of Health of the Russian Federation
PhD, Associate Professor, Department of Pathological Physiology,
Orenburg
Russian FederationY. A. Sarycheva
Orenburg State Medical University, Ministry of Health of the Russian Federation
PhD, Associate Professor, Department of Pathological Physiology,
Orenburg
Russian FederationA. A. Tokareva
Orenburg State Medical University, Ministry of Health of the Russian Federation
Assistant of the Department of Pathological Physiology,
Orenburg
Russian FederationReferences
- Бухарин О. В. Персистенция патогенных бактерий. М.: Медицина, 1999, 322.
- Фролов Б. А., Железнова А. Д., Чайникова И. Н., Панфилова Т. В., Медведева И. П., Филиппова Ю. В., Смолягин. А. И. Защитный эффект милиацина при экспериментальной сальмонеллезной инфекции. Журн. Микробиол. 2013, 6, 3–8.
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