DETERMINATION OF THE LEVEL OF CYTOKINES IN BRONCHOALVEOLAR LAVAGE FLUID IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONAY DISEASE
- 作者: Ryabova L.V.1, Nikonova S.E.2
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隶属关系:
- Federal state budgetary educational institution of higher education “South Ural State Medical University”
- Municipal Autonomous Healthcare Institution of the Order of the Red Banner of Labor “City Clinical Hospital No. 1”
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 506-508
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/120283
- DOI: https://doi.org/10.31857/S102872210006946-5
- ID: 120283
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详细
19 patients were diagnosed with stage III–IV COPD, the smoking experience was 39.1±1.94 years. In this group of patients, a study of cytokines IL-1β, IL-6, IL-8, IL-10, TNF-α in bronchoalveolar lavage fluid was carried out by the method of enzyme-linked immunosorbent assay. Disequilibrium of cytokins was found, which was appeared by statistically significant raising of proinfl ammatory cytokines IL-1β, IL-6, IL-8, and statistically significant lowering for anti-inflammatory cytokines IL-10, so that proves presence of chronic persistent infl ammations in the bronchial tree.
作者简介
L. Ryabova
Federal state budgetary educational institution of higher education “South Ural State Medical University”
编辑信件的主要联系方式.
Email: fake@neicon.ru
holder of Habilitation degree in medicine, professor of Propaedeutics of Internal Diseases,
Chelyabinsk
俄罗斯联邦S. Nikonova
Municipal Autonomous Healthcare Institution of the Order of the Red Banner of Labor “City Clinical Hospital No. 1”
Email: nikonova_se@mail.ru
Head of the Pneumology Department,
Chelyabinsk
俄罗斯联邦参考
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- Пульмонология. Национальное руководство. Краткое издание / под ред. акад. РАМН А. Г. Чучалина. – М.: ГЭОТАР – Медиа, 2013. – 800 с.
- Хроническая обструктивная болезнь легких: Монография / под ред. Чучалина А. Г. (Серия монографий Российского респираторного общества). – М.: Издательский дом «Атмосфера», 2008. – 568 с., ил.
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