FEATURES OF CYTOKINE STATUS OF YOUNG MEN, PATIENTS WITH OSTEOARTHRITIS

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Abstract

In young men with osteoarthritis, hyperproduction of proinflammatory cytokines is observed, along with a decrease in IL-2 production at the earliest stage of inflammation.

About the authors

K. V. Raymuev

North-Western State Medical University named after I. I. Mechnikov

Ph.D., prof. Department of Therapy, Rheumatology, Examination of Temporary Disability and the Quality of Medical Care named after E. E. Eichwald,

Saint Petersburg

Russian Federation

M. E. Malyshev

Saint Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine;
Saint Petersburg State University

Author for correspondence.
Email: malyshev1972@yandex.ru

Doctor of Biological Sciences, Head of the City Laboratory of Immunogenetics and Serodiagnostics;

prof. Department of Maxillofacial Surgery and Surgical Dentistry,

Saint Petersburg

Russian Federation

V. I. Mazurov

North-Western State Medical University named after I. I. Mechnikov

Academician of the Russian Academy of Sciences, Professor, Head of the Department of Therapy, Rheumatology, Examination of Temporary Disability and the Quality of Medical Care named after E. E. Eichwald,

Saint Petersburg

Russian Federation

A. O. Bumay

Saint Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine;
Saint Petersburg State University

Junior Researcher Department of Ambulance;

Senior Lecturer Department of Maxillofacial Surgery and Surgical Dentistry,

Saint Petersburg

Russian Federation

T. G. Habirova

Saint Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine

head of the immunology laboratory,

Saint Petersburg

Russian Federation

References

  1. Мазуров В. И., Трофимова А. С., Трофимов Е. А. Факторы риска и некоторые аспекты патогенеза остеоартрита. Вестник СЗГМУ им. И. И. Мечникова. 2016; 2:116–125.
  2. Раймуев К. В., Ищенко А. М., Малышев М. Е. Провоспалительные и противовоспалительные цитокины в патогенезе остеоартрита. Вестник Северо-Западного государственного медицинского университета им. И. И. Мечникова. 2018, 10(3), 19–27.
  3. Goldring M. B., Otero M. Inflammation in osteoarthritis. Current opinion in rheumatology. 2011;23(5): 471–478.

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Copyright (c) 2019 Raymuev K.V., Malyshev M.E., Mazurov V.I., Bumay A.O., Habirova T.G.

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