PROGNOSTIC VALUE OF INTRACELLULAR ADHESION MOLECULES IN HEMOLYTIC-UREMIC SYNDROME

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Abstract

The article presents the results of a study assessing the diagnostic and prognostic significance of determining the content of soluble intercellular adhesion molecules in children with typical and atypical hemolytic-uremic syndrome.

About the authors

O. V. Moskalets

Moscow Regional Research and Clinical Institute named after M. F. Vladimirskij

Author for correspondence.
Email: 6816000@mail.ru

PhD, Leading Researcher, Research Laboratory,

Moscow 

Russian Federation

T. E. Pankratenko

Moscow Regional Research and Clinical Institute named after M. F. Vladimirskij

PhD, Assistant Professor of Department of Transplantology, Nephrology and Artificial Organs, Faculty of Advanced Medical Studies,

Moscow 

Russian Federation

References

  1. Talarico V., Aloe M., Monzani A., Miniero R., Bona G. Hemolytic uremic syndrome in children. Minerva Pediatr.2016; 68(6), 441–445.
  2. Keir L. S., Marks S. D., Kim J. J. Shigatoxin-associated hemolytic uremic syndrome: current molecular mechanisms and future therapies. Drug Des Devel Ther. 2012;6, 195–208.
  3. Loirat C., Frémeaux-Bacchi V. Atypical hemolytic uremic syndrome. Orphanet J Rare Dis. 2011; 6, 60–66.
  4. Москалец О. В. Молекулы клеточной адгезии ICAM-1 и VCAM-1 при инфекционной патологии. Тихоокеанский медицинский журнал. 2018, 2, 21–25.
  5. Carter S., Hewitt I., Kausman J. Long-term remission with eculizumab in atypical haemolytic uraemic syndrome. Nephrology(Cariton). 2017;22 (Suppl.1),7–10.

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Copyright (c) 2019 Moskalets O.V., Pankratenko T.E.

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