THE EXPRESIION OF NCR RECEPTORS BY ENDOMETRIAL NATURAL KILLERS IN WOMEN WITH UTERINE LEIOMYOMA
- 作者: Malyshkina D.A.1, Antsiferova Y.S.2, Dolgushina N.V.1
-
隶属关系:
- B.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare of the Russian Federation
- Ivanovo’s Research Institute of Maternity and Childhood named after V. N. Gorodkov Ministry of Healthcare of the Russian, Ivanovo
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 391-393
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/120097
- DOI: https://doi.org/10.31857/S102872210006907-2
- ID: 120097
如何引用文章
全文:
详细
The patients with uterine leiomyoma demonstrate the signifi cant elevation of NKp44 and NKp46 expression by endometrial CD56+ lymphocytes. The high proliferation of leiomyoma is not associated with changes of NCR expression by endometrial NK. In the case of low proliferation the level of NK, CD56+NKp46+ and CD56+NKp46+NKp44+ lymphocytes is increased in comparison to the control group and group of patients with high expression of Ki67 in leiomyoma tissue.
作者简介
D. Malyshkina
B.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare of the Russian Federation
编辑信件的主要联系方式.
Email: fake@neicon.ru
MD, Student,
Moscow
俄罗斯联邦Yu. Antsiferova
Ivanovo’s Research Institute of Maternity and Childhood named after V. N. Gorodkov Ministry of Healthcare of the Russian, Ivanovo
Email: niimid.immune@mail.ru
BD, Leadingscientific worker of the Laboratory of Clinical immunology,
Ivanovo
俄罗斯联邦N. Dolgushina
B.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare of the Russian Federation
Email: fake@neicon.ru
MD, PhD, Head of R&D Department,
Moscow
俄罗斯联邦参考
- Commandeur A. E., Styer A. K., Teixeira J. M. Epidemiological and genetic clues for molecular mechanisms involved in uterine leiomyoma development and growth. Hum Reprod Update. 2015, 21(5), 593–615.
- Antsiferova Y., Sotnikova N., Voronin D., Malyshkina A., Kirsanov A. Macrophages subsets in the endometrium of women with uterine leiomyoma. Am J Reprod Immunol. 2015, 73, Issue Supplement S1, 21.
- Pazina T., Shemesh A., Brusilovsky M., Porgador A., Campbell K. S. Regulation of the Functions of Natural Cytotoxicity Receptors by Interactions with Diverse Ligands and Alterations in Splice Variant Expression. Front Immunol. 2017, 30 (8),369.
- Миома матки / под ред. И. С. Сидоровой. – М.: МИА, 2003. – 256 с.
补充文件
