CYTOKINES' RESPONSE UNDER SEPSIS AND TRAUMA
- Authors: Zotova N.V.1,2, Gusev E.Y.1,2, Zubova T.E.1
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Affiliations:
- Institute of Immunology and Physiology of UB RAS
- Auto Federal State Autonomous Educational Institution of Higher Professional Education "Ural Federal University named after the first President of Russia B. N. Yeltsin"
- Issue: Vol 20, No 2 (2017)
- Pages: 336-337
- Section: Articles
- URL: https://journals.rcsi.science/1028-7221/article/view/120068
- ID: 120068
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Abstract
We detected rates of IL-6, -8, -10, TNF-α, and CRP in plasma of patients with sepsis and polytrauma at 1-2nd and 5-7th days after admission in ICU. All patients were divided into groups with/ without MODS development. A rise in mediator levels in all groups of patients were identified. The maximum of detected increasing was in patients with MODS. There was not a clear cytokines-etiological agent dependence.
About the authors
N. V. Zotova
Institute of Immunology and Physiology of UB RAS; Auto Federal State Autonomous Educational Institution of Higher Professional Education "Ural Federal University named after the first President of Russia B. N. Yeltsin"
Author for correspondence.
Russian Federation
E. Yu. Gusev
Institute of Immunology and Physiology of UB RAS; Auto Federal State Autonomous Educational Institution of Higher Professional Education "Ural Federal University named after the first President of Russia B. N. Yeltsin"Russian Federation
T. E. Zubova
Institute of Immunology and Physiology of UB RASRussian Federation
References
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- Singer M., Deutschman C. S., Seymour C. W., Shankar-Hari M., Annane D., et al. The Third International Consensus Defi nitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016, 315 (8), 801-810.
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