EFFICIENCY OF THE APPLICATION OF IMMUNE CORRECTIVE THERAPY IN OUTSIDE GENITAL ENDOMETRIOSIS
- Authors: Magzumova N.M.1, Musakhodzhaeva D.A.2, Ismoilova D.U.1
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Affiliations:
- Tashkent Medical Academy
- Institute of Human Immunology and Genomics, Academy of Sciences of the Republic of Uzbekistan
- Issue: Vol 22, No 2-1 (2019)
- Pages: 385-387
- Section: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/120060
- DOI: https://doi.org/10.31857/S102872210006905-0
- ID: 120060
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Abstract
38 women with external genital endometriosis (NGE) of II‒III degree were examined, which consisted of 2 groups: 1st group ‒ 20 patients in whom Roncoleukin was injected into the peritoneal cavity during laparoscopy, and after surgery for 2nd, 4th Every day and then ‒ 2 times a week for 3 weeks was administered intravenously at a dosage of 0.5 mg. The second group consisted of 18 women with NGE, in whom, after laparoscopy, buserelin depot was administered as an anti-relapse therapy with 3.75 mg intramuscularly once a month for 6 months. Cytokine levels (IL-1β, IL-2, IL-6, IL-8, TNFα and IFNγ) were studied in the peritoneal fl uid in women with HEG before and after treatment. An imbalance of the studied cytokines was detected in patients, which was restored after the application of immunocorrection.
Keywords
About the authors
N. M. Magzumova
Tashkent Medical Academy
Author for correspondence.
Email: dilym@mail.ru
MD, Professor of the Department of Obstetrics and Gynecology,
Tashkent
Russian FederationD. A. Musakhodzhaeva
Institute of Human Immunology and Genomics, Academy of Sciences of the Republic of Uzbekistan
Email: fake@neicon.ru
Dr. of Biological Sciences, Head of Reproductive Immunology,
Tashkent
Russian FederationD. U. Ismoilova
Tashkent Medical Academy
Email: fake@neicon.ru
ass. Kaf. GP preparation of the Urgench branch,
Tashkent
Russian FederationReferences
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